PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22689051-0 2013 Myricetin attenuates lipopolysaccharide-stimulated activation of mouse bone marrow-derived dendritic cells through suppression of IKK/NF-kappaB and MAPK signalling pathways. myricetin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 134-143 31712142-5 2020 Moreover, Myr could efficiently mediate multiple signaling pathways, displaying not only the regulation of caspase-3/9 and P53 protein, inhibition of toll-like receptor 4 (TLR4)-nuclear factor-kappa B (NF-kappaB) activation, and -mitogen-activated protein kinase (MAPK), but also the increase of heme oxygenase-1 (HO-1) and nuclear factor-erythroid 2-related factor 2 (Nrf2) expression, as well as induction of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase (ACC) phosphorylation in mice with LPS/D-GalN-induced FH. myricetin 10-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 202-211 30746687-9 2019 Collectively, these data suggested that myricetin effectively ameliorated the inflammatory response by inhibiting the AKT/IKK/NF-kappaB signaling pathway and repairing the integrity of blood-milk barrier in LPS-induced mice mastitis. myricetin 40-49 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 126-135 31712142-9 2020 Taken together, Myr exhibits a protective role against LPS/D-GalN-induced FH by suppressing hepatic apoptosis, inflammation, and oxidative stress, likely involving in the regulation of apoptosis-related protein, TLR4-NF-kappaB/-MAPK and NLRP3 inflammasome, and AMPK-Nrf2/HO-1 signaling pathway. myricetin 16-19 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 217-226 29147465-0 2017 Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IkappaBalpha/NFkappaB and Enhancing Nrf2/HO-1. myricetin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 108-116 21385599-9 2011 In addition, myricetin, a natural inhibitor of the MEK/ERK signal pathway, reduced AA-induced activation of the COX-2 promoter as well as activation of AP-1 and NF-kappaB. myricetin 13-22 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 161-170 15832812-6 2005 Furthermore, activation of macrophages by LPS resulted in markedly enhanced binding activity to the NF-kappaB site, which significantly decreased upon addition of myricetin, indicating that myricetin inhibited IL-12 production in LPS-activated macrophages via the down-regulation of NF-kappaB binding activity. myricetin 163-172 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 100-109 15832812-6 2005 Furthermore, activation of macrophages by LPS resulted in markedly enhanced binding activity to the NF-kappaB site, which significantly decreased upon addition of myricetin, indicating that myricetin inhibited IL-12 production in LPS-activated macrophages via the down-regulation of NF-kappaB binding activity. myricetin 163-172 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 283-292 15832812-6 2005 Furthermore, activation of macrophages by LPS resulted in markedly enhanced binding activity to the NF-kappaB site, which significantly decreased upon addition of myricetin, indicating that myricetin inhibited IL-12 production in LPS-activated macrophages via the down-regulation of NF-kappaB binding activity. myricetin 190-199 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 100-109 15832812-6 2005 Furthermore, activation of macrophages by LPS resulted in markedly enhanced binding activity to the NF-kappaB site, which significantly decreased upon addition of myricetin, indicating that myricetin inhibited IL-12 production in LPS-activated macrophages via the down-regulation of NF-kappaB binding activity. myricetin 190-199 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 283-292