PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35192944-7	2022	Further studies showed that treatment of human neuroblastoma SH-SY5Y cells with Myricetin increased HIF-1alpha protein levels.	myricetin	80-89	hypoxia inducible factor 1 subunit alpha	Homo sapiens	100-110	
22245592-6	2012	We also found that myricetin, quercetin, piceatannol and resveratrol up-regulated HIF-1alpha and down-regulated c-Myc, PHD2 and beta-catenin expressions via SIRT1 activation, in a manner that mimics hypoxic preconditioning.	myricetin	19-28	hypoxia inducible factor 1 subunit alpha	Homo sapiens	82-92	
26113875-4	2015	It was observed that galangin and myricetin inhibited secretion of the key angiogenesis mediator vascular endothelial growth factor (VEGF) and decreased levels of p-Akt, p-70S6K and hypoxia-inducible factor-1alpha (HIF-1alpha) proteins in A2780/CP70 and OVCAR-3 cells.	myricetin	34-43	hypoxia inducible factor 1 subunit alpha	Homo sapiens	182-213	
26113875-4	2015	It was observed that galangin and myricetin inhibited secretion of the key angiogenesis mediator vascular endothelial growth factor (VEGF) and decreased levels of p-Akt, p-70S6K and hypoxia-inducible factor-1alpha (HIF-1alpha) proteins in A2780/CP70 and OVCAR-3 cells.	myricetin	34-43	hypoxia inducible factor 1 subunit alpha	Homo sapiens	215-225	
26113875-5	2015	Transient transfection experiments showed that galangin and myricetin inhibited secretion of VEGF by the Akt/p70S6K/ HIF-1alpha pathway.	myricetin	60-69	hypoxia inducible factor 1 subunit alpha	Homo sapiens	117-127	
26113875-6	2015	Moreover, a novel pathway, p21/HIF-1alpha/VEGF, was found to be involved in the inhibitory effect of myricetin on angiogenesis in OVCAR-3 cells.	myricetin	101-110	hypoxia inducible factor 1 subunit alpha	Homo sapiens	31-41