PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12435803-4	2002	The D(2)DR antagonist spiperone blocked quinpirole-elicited PTP inhibition, and the D(1) receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (SKF38393) did not inhibit PTP activity, indicating that PTP inhibition is a specific effect mediated by stimulation of D(2)DR. We further discovered that striatal mitogen-activated protein kinase phosphatase (MKP), a protein phosphatase that is responsible for ERK dephosphorylation, is inhibited in response to D(2)DR stimulation in 6-OHDA-lesioned rats.	Spiperone	22-31	protein tyrosine phosphatase, non-receptor type 1	Rattus norvegicus	60-63