PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8272199-6	1993	Pyridostigmine pretreatment significantly increased the ACTH response to CRH in controls but not in patients.	Pyridostigmine Bromide	0-14	corticotropin releasing hormone	Homo sapiens	73-76	
1543015-0	1992	Activation of cholinergic tone by pyridostigmine reverses the inhibitory effect of corticotropin-releasing hormone on the growth hormone-releasing hormone-induced growth hormone secretion.	Pyridostigmine Bromide	34-48	corticotropin releasing hormone	Homo sapiens	83-114	
1543015-2	1992	In an attempt to clarify the mechanism of the CRH action, we have studied the effect of enhanced cholinergic tone induced by pyridostigmine on the CRH inhibition of the GH response to GHRH in a group of six normal men and six normal women.	Pyridostigmine Bromide	125-139	corticotropin releasing hormone	Homo sapiens	147-150	
1543015-6	1992	Pyridostigmine (60 mg) given orally at the same time of CRH administration (60 min before GHRH) reversed the CRH inhibition of GHRH-induced GH secretion (GH peaks 35.3 +/- 8.2 micrograms/l in men and 35 +/- 3.3 micrograms/l in women) with a response not significantly different to that seen in the pyridostigmine plus GHRH test.	Pyridostigmine Bromide	0-14	corticotropin releasing hormone	Homo sapiens	56-59	
1543015-6	1992	Pyridostigmine (60 mg) given orally at the same time of CRH administration (60 min before GHRH) reversed the CRH inhibition of GHRH-induced GH secretion (GH peaks 35.3 +/- 8.2 micrograms/l in men and 35 +/- 3.3 micrograms/l in women) with a response not significantly different to that seen in the pyridostigmine plus GHRH test.	Pyridostigmine Bromide	0-14	corticotropin releasing hormone	Homo sapiens	109-112	
1543015-6	1992	Pyridostigmine (60 mg) given orally at the same time of CRH administration (60 min before GHRH) reversed the CRH inhibition of GHRH-induced GH secretion (GH peaks 35.3 +/- 8.2 micrograms/l in men and 35 +/- 3.3 micrograms/l in women) with a response not significantly different to that seen in the pyridostigmine plus GHRH test.	Pyridostigmine Bromide	298-312	corticotropin releasing hormone	Homo sapiens	109-112