PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32587126-10	2020	High fructose intake increased the expression of angiotensinogen in the liver; angiotensin-converting enzyme in the lungs; and renin, angiotensin II type 1a receptor (AT1aR), and angiotensin II type 1b receptor (AT1bR) in the kidneys.	Fructose	5-13	angiotensin I converting enzyme	Rattus norvegicus	79-108	
27121972-0	2016	Fructose-rich diet induces gender-specific changes in expression of the renin-angiotensin system in rat heart and upregulates the ACE/AT1R axis in the male rat aorta.	Fructose	0-8	angiotensin I converting enzyme	Rattus norvegicus	130-133	
19696478-1	2009	BACKGROUND: Both ACE inhibitors and allopurinol have been shown to partially prevent metabolic syndrome induced by fructose.	Fructose	115-123	angiotensin I converting enzyme	Rattus norvegicus	17-20	
15055257-0	2004	Regulation of skeletal muscle peroxisome proliferator-activated receptor gamma expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats.	Fructose	150-158	angiotensin I converting enzyme	Rattus norvegicus	106-135	
17079949-11	2006	This suggests that ACE inhibition upregulates the eNOS isoform locally, increases vasopermeability of the pancreas, and can therefore result in local edema in the fructose-fed insulin-resistant rat model.	Fructose	163-171	angiotensin I converting enzyme	Rattus norvegicus	19-22	
15004411-12	2004	These results suggest that, in insulin-resistant rats induced by the high-fructose feeding, an ACE inhibitor, such as imidapril, can improve the whole-body insulin-mediated glucose disposal and that this effect of imidapril is essentially linked to increased activation of NO-pathway.	Fructose	74-82	angiotensin I converting enzyme	Rattus norvegicus	95-98	
15055257-1	2004	The purpose of this study was to examine the effects of chronic exercise training and angiotensin-converting enzyme (ACE) inhibition on peroxisome proliferator-activated receptor gamma (PPAR gamma) expression in fat and skeletal muscle in fructose-fed spontaneously hypertensive rats (SHR).	Fructose	239-247	angiotensin I converting enzyme	Rattus norvegicus	117-120	
8781750-2	1996	The present study was designed to clarify the mechanism by which ACE inhibitors affect glucose metabolism in fructose (FRU)-fed Wistar rats with hypertension, glucose intolerance and hyperinsulinemia.	Fructose	109-117	angiotensin I converting enzyme	Rattus norvegicus	65-68	
8781750-2	1996	The present study was designed to clarify the mechanism by which ACE inhibitors affect glucose metabolism in fructose (FRU)-fed Wistar rats with hypertension, glucose intolerance and hyperinsulinemia.	Fructose	119-122	angiotensin I converting enzyme	Rattus norvegicus	65-68	
9072423-0	1995	Effect of angiotensin-converting enzyme inhibitors on fructose induced hypertension and hyperinsulinaemia in rats.	Fructose	54-62	angiotensin I converting enzyme	Rattus norvegicus	10-39	
7619347-1	1995	This study was designed to investigate the effects of angiotensin II (AII) receptor antagonist and angiotensin converting enzyme (ACE) inhibitor on insulin resistance, and the mechanism by which ACE inhibitor improves insulin-dependent glucose uptake (insulin sensitivity) in an insulin-resistant hypertensive rat model (fructose-fed rats, FFR) and in essential hypertensives (EHT).	Fructose	321-329	angiotensin I converting enzyme	Rattus norvegicus	195-198	
34656062-6	2021	The results show that type-2 diabetes induction with fructose and streptozotocin led to increased blood glucose levels, decreased insulin levels and cardiac antioxidant enzyme activities, increased malondialdehyde levels, cardiac biomarkers and pro-inflammatory cytokines levels, resulted in abnormal lipid profile, increased blood pressure and angiotensin-converting enzyme (ACE) activity, and decreased plasma endothelial nitric oxide synthase (eNOS) concentration.	Fructose	53-61	angiotensin I converting enzyme	Rattus norvegicus	345-374	
34656062-6	2021	The results show that type-2 diabetes induction with fructose and streptozotocin led to increased blood glucose levels, decreased insulin levels and cardiac antioxidant enzyme activities, increased malondialdehyde levels, cardiac biomarkers and pro-inflammatory cytokines levels, resulted in abnormal lipid profile, increased blood pressure and angiotensin-converting enzyme (ACE) activity, and decreased plasma endothelial nitric oxide synthase (eNOS) concentration.	Fructose	53-61	angiotensin I converting enzyme	Rattus norvegicus	376-379