PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17051422-4	2007	Biologically relevant [GSNO]/[HXK] caused a significant decrease in V(max) with glucose (but not with fructose), along with oxidation of 5 Met and nitration of 4 Tyr.	Fructose	102-110	hexokinase 1	Homo sapiens	30-33	
20453072-2	2010	Glucose and fructose phosphorylations appear to rely exclusively on glucokinase and hexokinase.	Fructose	12-20	hexokinase 1	Homo sapiens	84-94	
20453072-5	2010	Hexokinase showed a high efficiency for fructose activation but also activated glucose and mannose.	Fructose	40-48	hexokinase 1	Homo sapiens	0-10	
15589764-3	2004	Soft-landing efficiency for multiply-charged hexokinase ions was found to be some four times higher for a glycerol/fructose liquid surface than for a fluorinated self-assembled monolayer surface.	Fructose	115-123	hexokinase 1	Homo sapiens	45-55	
11545174-2	2000	For over half a century the means by which fructose is metabolized by sperm has been assumed to be by an initial phosphorylation catalysed by hexokinase, but this has never been substantiated.	Fructose	43-51	hexokinase 1	Homo sapiens	142-152	
11545174-3	2000	In the present study, by comparing the metabolism of glucose and fructose by both whole boar sperm and hypotonically treated cells, it is confirmed that fructose is phosphorylated by hexokinase to produce fructose 6-phosphate.	Fructose	153-161	hexokinase 1	Homo sapiens	183-193	
11545174-3	2000	In the present study, by comparing the metabolism of glucose and fructose by both whole boar sperm and hypotonically treated cells, it is confirmed that fructose is phosphorylated by hexokinase to produce fructose 6-phosphate.	Fructose	65-73	hexokinase 1	Homo sapiens	183-193	
9298844-3	1997	The first metabolic step for all sugars, including fructose being generated by enzymatic oxidation of sorbitol, is phosphorylation by hexokinase.	Fructose	51-59	hexokinase 1	Homo sapiens	134-144	
3631962-0	1987	Inhibition of hexokinase activity by a fructose 2,6-bisphosphate-dependent cytosolic protein from liver.	Fructose	39-47	hexokinase 1	Homo sapiens	14-24	
3346690-7	1988	Further metabolic studies suggest that the block in glucose metabolism is by-passed via an enhanced phosphorylation of fructose by the abnormal hexokinase.	Fructose	119-127	hexokinase 1	Homo sapiens	144-154	
2826162-1	1987	In tumoral islet cells (RINm5F line) the phosphorylation of D-fructose is catalyzed by hexokinase rather than fructokinase.	Fructose	60-70	hexokinase 1	Homo sapiens	87-97	
1599419-2	1992	In human erythrocytes, the first step in the metabolism of fructose is generally thought to be phosphorylation to fructose 6-phosphate catalysed by hexokinase.	Fructose	59-67	hexokinase 1	Homo sapiens	148-158	
33762003-16	2021	GLUT5 permitted fructose to flux through glycolysis using hexokinase (HK) and not ketohexokinase (KHK).	Fructose	16-24	hexokinase 1	Homo sapiens	58-68	
33762003-16	2021	GLUT5 permitted fructose to flux through glycolysis using hexokinase (HK) and not ketohexokinase (KHK).	Fructose	16-24	hexokinase 1	Homo sapiens	70-72	
6416107-5	1983	The hexokinase procedures allows the measurement of fructose, 2,5-anhydromannitol, and 2,5-anhydromannose.	Fructose	52-60	hexokinase 1	Homo sapiens	4-14	
5682290-0	1968	Kinetic studies of solubilized brain hexokinase with D-fructose as a substrate.	Fructose	53-63	hexokinase 1	Homo sapiens	37-47	
33823-3	1979	Parenchymal hexokinase is more susceptible to glucose inhibition, can tolerate greater variations in the ATP concentration, is inhibited by increasing concentrations of fructose and potassium, and showed greater activity on the lower pH values.	Fructose	169-177	hexokinase 1	Homo sapiens	12-22	
18098550-0	1948	Studies on glycolysis of brain preparations; affinity of hexokinase for glucose and fructose.	Fructose	84-92	hexokinase 1	Homo sapiens	57-67	
29616058-3	2018	Both sucrose-cleaving enzymes yield free fructose, which must be phosphorylated by either fructokinase (FRK) or hexokinase (HXK).	Fructose	41-49	hexokinase 1	Homo sapiens	112-122	
29616058-3	2018	Both sucrose-cleaving enzymes yield free fructose, which must be phosphorylated by either fructokinase (FRK) or hexokinase (HXK).	Fructose	41-49	hexokinase 1	Homo sapiens	124-127	
29616058-4	2018	The affinity of FRK to fructose is much higher than that of HXK, making FRKs central for fructose metabolism.	Fructose	89-97	hexokinase 1	Homo sapiens	60-63	
28405835-2	2017	RESULTS: Fructose at 1 M (180 g l-1) was converted to 0.8 M (144 g l-1) tagatose by a three-step enzymatic cascade reaction, involving hexokinase, plus ATP, fructose-1,6-biphosphate aldolase, phytase, over 16 h with a productivity of 9 g l-1 h-1.	Fructose	9-17	hexokinase 1	Homo sapiens	135-145