PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16229464-0 2005 Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: dimethylargininase and peptidylarginine deiminase. 2-chloroacetamidine 77-96 peptidyl arginine deiminase 4 Homo sapiens 121-147 16229464-3 2005 Here, we find that 2-chloroacetamidine irreversibly inhibits both DDAH from Pseudomonas aeruginosa and human PAD4 in a time- and concentration-dependent manner, despite the nonoverlapping substrate specificities and low levels of amino acid identity of their catalytic domains. 2-chloroacetamidine 19-38 peptidyl arginine deiminase 4 Homo sapiens 109-113