PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18818743-0 2008 Enhanced Glucose Requirement in Human Hepatoma-derived HuH-7 Cells by Forced Expression of the bcl-2 Gene. Glucose 9-16 MIR7-3 host gene Homo sapiens 55-60 18818743-3 2008 HuH-7/bcl-2 cells consumed glucose at a higher rate, exhausted the available cellular ATP and died on day 9, while HuH-7/neo cells were still alive for 10 days under the same condition where cells were cultured without replenishment of the medium. Glucose 27-34 MIR7-3 host gene Homo sapiens 0-5 27458503-0 2016 Lipogenesis in Huh7 cells is promoted by increasing the fructose: Glucose molar ratio. Glucose 66-73 MIR7-3 host gene Homo sapiens 15-19 18057713-2 2007 In the present study, we found that treatment of HuH-7 human hepatoma cells with high glucose or the protein O-N-acetylglucosaminidase (O-GlcNAcase) inhibitor O-(2-acetoamide-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc) increased the cell surface expression of E-selectin. Glucose 86-93 MIR7-3 host gene Homo sapiens 49-54 22358595-6 1997 When the 6 cell lines were grown in a submerged culture with 0.6 g/l of CPBs, Huh 7 had the lowest cell concentration of 0.54 x 10(6) cells/ml, and the highest activities of ammonia consumption and urea and glucose production (1.38 mu mol NH(3), 99 nmol urea, and 14.5 nmol glucose/10(6)cells/h). Glucose 207-214 MIR7-3 host gene Homo sapiens 78-83 22358595-6 1997 When the 6 cell lines were grown in a submerged culture with 0.6 g/l of CPBs, Huh 7 had the lowest cell concentration of 0.54 x 10(6) cells/ml, and the highest activities of ammonia consumption and urea and glucose production (1.38 mu mol NH(3), 99 nmol urea, and 14.5 nmol glucose/10(6)cells/h). Glucose 274-281 MIR7-3 host gene Homo sapiens 78-83 33354836-8 2021 Glucose addition significantly further decreased pHe in hyperglycolytic cell lines (VX2, HepG2, and Huh7, by 0.28, 0.06, and 0.11, respectively, all p < 0.001), whereas 3-bromopyruvate normalized tumor pHe in a dose-dependent manner without affecting viability. Glucose 0-7 MIR7-3 host gene Homo sapiens 100-104 32409919-6 2020 Insulin-resistant Huh7 (Huh7-IR) showed a reduction in Glut2, glycogen levels, and glucose uptake stimulated by insulin or tyrosine phosphorylation from the beta-fraction of insulin receptor post-insulin stimulation, with an increase of glucose production and lipid intracellular content. Glucose 83-90 MIR7-3 host gene Homo sapiens 18-22 32409919-6 2020 Insulin-resistant Huh7 (Huh7-IR) showed a reduction in Glut2, glycogen levels, and glucose uptake stimulated by insulin or tyrosine phosphorylation from the beta-fraction of insulin receptor post-insulin stimulation, with an increase of glucose production and lipid intracellular content. Glucose 83-90 MIR7-3 host gene Homo sapiens 24-28 32409919-6 2020 Insulin-resistant Huh7 (Huh7-IR) showed a reduction in Glut2, glycogen levels, and glucose uptake stimulated by insulin or tyrosine phosphorylation from the beta-fraction of insulin receptor post-insulin stimulation, with an increase of glucose production and lipid intracellular content. Glucose 237-244 MIR7-3 host gene Homo sapiens 18-22 32409919-6 2020 Insulin-resistant Huh7 (Huh7-IR) showed a reduction in Glut2, glycogen levels, and glucose uptake stimulated by insulin or tyrosine phosphorylation from the beta-fraction of insulin receptor post-insulin stimulation, with an increase of glucose production and lipid intracellular content. Glucose 237-244 MIR7-3 host gene Homo sapiens 24-28 32643289-3 2020 METHODS: Huh7 cells were cultured in 11 mM glucose and 2% human serum (HS) for 7 days before additional sugars and fatty acids (FAs), either with 200 microM FAs (low fat low sugar; LFLS), 5.5 mM fructose + 200 microM FAs (low fat high sugar; LFHS), or 5.5 mM fructose + 800 microM FAs (high fat high sugar; HFHS), were added for 7 days. Glucose 43-50 MIR7-3 host gene Homo sapiens 9-13 17189875-3 2007 HuH7 human hepatocyte cells were treated with high glucose alone or in combination with proinflammatory cytokines, and the effects on the activity of the transcription factor nuclear factor kappa-B (NF-kappaB), which mediates the expression of acute-phase and coagulation-related genes, were examined. Glucose 51-58 MIR7-3 host gene Homo sapiens 0-4 19002963-3 2000 Inthe case of Huh 7 cells, glucose was consumed rapidly,the concentration of ammonia increased and that of urearemained the same. Glucose 27-34 MIR7-3 host gene Homo sapiens 14-19 19002963-4 2000 The major energy sources amongmedium components were glutamine for the primary cellsand glucose for Huh 7 cells, although the primaryhepatocytes may utilize intracellular glycogen asenergy source. Glucose 88-95 MIR7-3 host gene Homo sapiens 100-105 28663370-8 2017 In the presence of exogenous glucose, starvation decreased the Crabtree effect in Huh7 and C2C12 cells and abrogated it in mouse neuroblastoma N2A cells. Glucose 29-36 MIR7-3 host gene Homo sapiens 82-86 27458503-2 2016 METHODS: Hepatocytes (Huh7), demonstrating glucose and fructose uptake and lipid biosynthesis, were incubated in culture media containing either glucose alone (0.65-0.72 mmol/L) or isosmolar monosaccharide (0.72 mmol/L) comprising fructose:glucose (F:G) molar ratios ranging from 0.58-0.67. Glucose 43-50 MIR7-3 host gene Homo sapiens 22-26 27138141-4 2016 Meanwhile, luciferase reporter assay proved that the PKM2 is the target of miR-122, and we reported that the glucose metabolism is significantly up-regulated in Huh7/R cells. Glucose 109-116 MIR7-3 host gene Homo sapiens 161-165 26029722-3 2015 After transfection of the Huh7ins cells with human islet glucokinase, the resultant Melligen cells secreted insulin in response to glucose within the physiological range; commencing at 4.25 mmol/l. Glucose 131-138 MIR7-3 host gene Homo sapiens 26-30 21072897-9 2010 The growth indices for the control, Glc-AGE, and Glycer-AGE were 1.06 +- 0.08, 0.99 +- 0.04, and 1.38 +- 0.05, respectively, in HuH7 (P = 0.037), and were 1.03 +- 0.04, 1.04 +- 0.03, and 1.07 +- 0.05, respectively, in HepG2 (P > 0.05). Glucose 36-39 MIR7-3 host gene Homo sapiens 128-132 26380295-6 2015 High glucose promoted HuH7 cell proliferation but not that of HepG2 cell line. Glucose 5-12 MIR7-3 host gene Homo sapiens 22-26 21084851-1 2009 Previously, the insulin producing liver cell line HUH7-ins has been shown to synthesize, store and secrete insulin in response to glucose via secretory granules. Glucose 130-137 MIR7-3 host gene Homo sapiens 50-54