PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32814902-2 2020 Here we generate human islet-like organoids (HILOs) from induced pluripotent stem cells and show that non-canonical WNT4 signalling drives the metabolic maturation necessary for robust ex vivo glucose-stimulated insulin secretion. Glucose 193-200 Wnt family member 4 Homo sapiens 116-120 30935943-2 2019 Studies have shown that there is decrease in the secretion of Wnt proteins including Wnt4, 5a and Wnt 6 during high glucose concentration or diabetic conditions, which leads to decreased translocation of beta-catenin to nucleus. Glucose 116-123 Wnt family member 4 Homo sapiens 85-89