PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29455547-8	2018	SFRP-4 was significantly correlated with fasting glucose, HbA1c, and triglyceride levels.	Glucose	49-56	secreted frizzled related protein 4	Homo sapiens	0-6	
35290144-10	2022	SFRP4 expression was upregulated in a high-glucose-stimulated H/R cardiomyocyte model.	Glucose	43-50	secreted frizzled related protein 4	Homo sapiens	0-5	
35290144-11	2022	The interference of SFRP4 promoted cell viability, inhibited the inflammatory and oxidative stress response of H/R cardiomyocytes induced by high glucose.	Glucose	146-153	secreted frizzled related protein 4	Homo sapiens	20-25	
35290144-13	2022	PTPN12 overexpression reversed the inhibitory effect of sh-SFRP4 on H/R cardiomyocyte damage induced by high glucose.	Glucose	109-116	secreted frizzled related protein 4	Homo sapiens	59-64	
29385093-6	2018	We demonstrate that sFRP4 has a prominent role in basal glucose uptake in CSCs derived from breast and prostate tumour cell lines.	Glucose	56-63	secreted frizzled related protein 4	Homo sapiens	20-25	
29385093-7	2018	We show that sFRP4 treatment on CSCs isolated with variable glucose content induces metabolic reprogramming by relocating metabolic flux to glycolysis or OXPHOS.	Glucose	60-67	secreted frizzled related protein 4	Homo sapiens	13-18	
29385093-8	2018	Altogether, sFRP4 treatment compromises cell proliferation and critically affects cell survival mechanisms such as viability, glucose transporters, pyruvate conversion, mammalian target of rapamycin, and induces CSC apoptosis under conditions of variable glucose content.	Glucose	126-133	secreted frizzled related protein 4	Homo sapiens	12-17	
26041556-0	2015	Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance.	Glucose	93-100	secreted frizzled related protein 4	Homo sapiens	27-62	
26041556-0	2015	Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance.	Glucose	160-167	secreted frizzled related protein 4	Homo sapiens	27-62	
26041556-7	2015	The serum SFRP4 levels were negatively correlated with AIR, AUC, GDI and HOMA-beta (P < 0.01) and were positively correlated with fasting plasma glucose, HbA1c, hs-CRP, and IL-1beta (P < 0.01).	Glucose	148-155	secreted frizzled related protein 4	Homo sapiens	10-15	
26041556-8	2015	Our study provides evidence that the concentrations of serum SFRP4 in T2DM and IGT subjects were increased and were correlated closely with glycose metabolic disorder, the first-phase of glucose-stimulated insulin secretion and chronic low-grade inflammation.	Glucose	187-194	secreted frizzled related protein 4	Homo sapiens	61-66	
23140642-6	2012	Elevated systemic SFRP4 caused reduced glucose tolerance through decreased islet expression of Ca(2+) channels and suppressed insulin exocytosis.	Glucose	39-46	secreted frizzled related protein 4	Homo sapiens	18-23	
25408147-3	2014	Here we characterized the relation of SFRP4 to glucose and triglyceride metabolism and outcomes in patients with stable coronary artery disease on statin treatment in the prospective Homburg Cream & Sugar Study (NCT00628524).	Glucose	47-54	secreted frizzled related protein 4	Homo sapiens	38-43