PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29455547-8 2018 SFRP-4 was significantly correlated with fasting glucose, HbA1c, and triglyceride levels. Glucose 49-56 secreted frizzled related protein 4 Homo sapiens 0-6 29385093-6 2018 We demonstrate that sFRP4 has a prominent role in basal glucose uptake in CSCs derived from breast and prostate tumour cell lines. Glucose 56-63 secreted frizzled related protein 4 Homo sapiens 20-25 29385093-7 2018 We show that sFRP4 treatment on CSCs isolated with variable glucose content induces metabolic reprogramming by relocating metabolic flux to glycolysis or OXPHOS. Glucose 60-67 secreted frizzled related protein 4 Homo sapiens 13-18 29385093-8 2018 Altogether, sFRP4 treatment compromises cell proliferation and critically affects cell survival mechanisms such as viability, glucose transporters, pyruvate conversion, mammalian target of rapamycin, and induces CSC apoptosis under conditions of variable glucose content. Glucose 126-133 secreted frizzled related protein 4 Homo sapiens 12-17 25408147-3 2014 Here we characterized the relation of SFRP4 to glucose and triglyceride metabolism and outcomes in patients with stable coronary artery disease on statin treatment in the prospective Homburg Cream & Sugar Study (NCT00628524). Glucose 47-54 secreted frizzled related protein 4 Homo sapiens 38-43 26041556-0 2015 Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance. Glucose 93-100 secreted frizzled related protein 4 Homo sapiens 27-62 26041556-0 2015 Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance. Glucose 160-167 secreted frizzled related protein 4 Homo sapiens 27-62 26041556-7 2015 The serum SFRP4 levels were negatively correlated with AIR, AUC, GDI and HOMA-beta (P < 0.01) and were positively correlated with fasting plasma glucose, HbA1c, hs-CRP, and IL-1beta (P < 0.01). Glucose 148-155 secreted frizzled related protein 4 Homo sapiens 10-15 26041556-8 2015 Our study provides evidence that the concentrations of serum SFRP4 in T2DM and IGT subjects were increased and were correlated closely with glycose metabolic disorder, the first-phase of glucose-stimulated insulin secretion and chronic low-grade inflammation. Glucose 187-194 secreted frizzled related protein 4 Homo sapiens 61-66 35290144-10 2022 SFRP4 expression was upregulated in a high-glucose-stimulated H/R cardiomyocyte model. Glucose 43-50 secreted frizzled related protein 4 Homo sapiens 0-5 23140642-6 2012 Elevated systemic SFRP4 caused reduced glucose tolerance through decreased islet expression of Ca(2+) channels and suppressed insulin exocytosis. Glucose 39-46 secreted frizzled related protein 4 Homo sapiens 18-23 35290144-11 2022 The interference of SFRP4 promoted cell viability, inhibited the inflammatory and oxidative stress response of H/R cardiomyocytes induced by high glucose. Glucose 146-153 secreted frizzled related protein 4 Homo sapiens 20-25 35290144-13 2022 PTPN12 overexpression reversed the inhibitory effect of sh-SFRP4 on H/R cardiomyocyte damage induced by high glucose. Glucose 109-116 secreted frizzled related protein 4 Homo sapiens 59-64