PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32900356-0 2021 Quercetin inhibits AQP1 translocation in high-glucose-cultured SRA01/04 cells through PI3K/Akt/mTOR Pathway. Glucose 46-53 aquaporin 1 (Colton blood group) Homo sapiens 19-23 32900356-12 2021 CONCLUSION: Quercetin significantly decreased the AQP1 elevation and prevented the change of AQP1 location through inhibiting the activation of the PI3K/Akt/mTOR signaling in high-glucose-cultured SRA01/04 cells, which might have the preventable and inhibitory effects on the early development of diabetic cataract. Glucose 180-187 aquaporin 1 (Colton blood group) Homo sapiens 93-97 32900356-1 2021 OBJECTIVE: To investigate the quercetin"s effects on Aquaporin 1 (AQP1) translocation in condition of high glucose and try to clarify the underlying mechanisms and provide new ideas for the treatment of diabetic cataract (DC). Glucose 107-114 aquaporin 1 (Colton blood group) Homo sapiens 53-64 32900356-1 2021 OBJECTIVE: To investigate the quercetin"s effects on Aquaporin 1 (AQP1) translocation in condition of high glucose and try to clarify the underlying mechanisms and provide new ideas for the treatment of diabetic cataract (DC). Glucose 107-114 aquaporin 1 (Colton blood group) Homo sapiens 66-70 32900356-8 2021 RESULTS: AQP1 protein was significantly increased at the time of 24 hour when exposured to high glucose (P<0.01). Glucose 96-103 aquaporin 1 (Colton blood group) Homo sapiens 9-13 31039249-7 2019 AQP1 expression from the Chiari malformation case showed an inverted polarity being expressed in the basal pole of the ChPE colocalizing with the glucose transporter 1 where this transporter is naturally located. Glucose 146-153 aquaporin 1 (Colton blood group) Homo sapiens 0-4 30958661-10 2019 Comparing cell lines after high glucose preconditioning, MeT-5A Pf was significantly higher than that of M14K and ZL34 MPM cells and the AQP1 inhibition effect was significant in MeT-5A and M14K cells. Glucose 32-39 aquaporin 1 (Colton blood group) Homo sapiens 137-141 27090529-4 2017 The osmotic conductance, i.e., milliliter of UF per gram of glucose absorbed, quantifies cooperation between small-pores and AQP1 channels. Glucose 60-67 aquaporin 1 (Colton blood group) Homo sapiens 125-129 19229826-0 2009 Effect of glucose degradation products, glucose-containing dialysate and icodextrin on AQP1 and eNOS expression in cultured endothelial cells. Glucose 40-47 aquaporin 1 (Colton blood group) Homo sapiens 87-91 23370527-9 2013 RESULTS: PTCs exposed to both high glucose and pioglitazone increased protein abundance of P-EGFR, NHE3, AQP1 and PPARgamma. Glucose 35-42 aquaporin 1 (Colton blood group) Homo sapiens 105-109 23370527-11 2013 High-glucose-induced increases in P-EGFR, NHE3 and AQP1 were decreased with PPARgamma siRNA. Glucose 5-12 aquaporin 1 (Colton blood group) Homo sapiens 51-55 25108283-0 2014 High glucose-induced hyperosmolarity impacts proliferation, cytoskeleton remodeling and migration of human induced pluripotent stem cells via aquaporin-1. Glucose 5-12 aquaporin 1 (Colton blood group) Homo sapiens 142-153 25108283-4 2014 We therefore investigated whether high glucose-induced hyperosmolarity impacts proliferation, migration, expression of pluripotency markers and actin skeleton remodeling in iPS cells in an AQP1-dependent manner. Glucose 39-46 aquaporin 1 (Colton blood group) Homo sapiens 189-193 25108283-12 2014 CONCLUSIONS: High glucose enhances human iPS cell proliferation and cytoskeletal remodeling due to hyperosmolarity-induced upregulation of AQP1. Glucose 18-25 aquaporin 1 (Colton blood group) Homo sapiens 139-143 20943045-0 2010 NA+/H+ exchanger 1- and aquaporin-1-dependent hyperosmolarity changes decrease nitric oxide production and induce VCAM-1 expression in endothelial cells exposed to high glucose. Glucose 169-176 aquaporin 1 (Colton blood group) Homo sapiens 24-35 19229826-3 2009 We aimed at examining the effect of peritoneal dialysis solutions (PDSs) and glucose degradation products (GDPs) on the expression of AQP1 and eNOS in cultured endothelial cells. Glucose 77-84 aquaporin 1 (Colton blood group) Homo sapiens 134-138 19229826-7 2009 Glucose-based PDS as well as icodextrin PDS significantly up-regulated basal AQP1 and eNOS mRNA. Glucose 0-7 aquaporin 1 (Colton blood group) Homo sapiens 77-81 15211447-9 2004 There was a significant correlation between AQP-1 expression and free-water transport after 1 hour of equilibration with 3.86% glucose in the PET (r = 0.753; P < 0.001). Glucose 127-134 aquaporin 1 (Colton blood group) Homo sapiens 44-49 15770929-1 2005 BACKGROUND: In peritoneal dialysis, approximately 40% of the total osmotic ultrafiltration (UF) induced by glucose can be predicted to be due to "free" water transport across aquaporin-1 (APQ-1). Glucose 107-114 aquaporin 1 (Colton blood group) Homo sapiens 175-186 17898873-4 2007 In cultured 9L gliosarcoma cells, AQP1 expression was induced by dexamethasone, platelet-derived growth factor, NaCl, hypoxia, D-glucose (but not L-glucose), and fructose. Glucose 127-136 aquaporin 1 (Colton blood group) Homo sapiens 34-38 17898873-5 2007 Induction of AQP1 expression correlated with the level of glycolysis, maximized by increasing medium D-glucose or fructose and decreasing O(2), and was quantified by measuring lactate dehydrogenase (LDH) activity and medium lactate concentration. Glucose 101-110 aquaporin 1 (Colton blood group) Homo sapiens 13-17 17898873-9 2007 Increased glucose metabolism at the tumor periphery may provide a scenario by which upregulation of AQP1, LDH, and cathepsin B contributes to acidification of the extracellular milieu and to invasive potential of glioma cells in perivascular space. Glucose 10-17 aquaporin 1 (Colton blood group) Homo sapiens 100-104 12218304-0 2002 D-glucose and NaCl enhance the expression of aquaporin-1: inhibition of both by cholera toxin. Glucose 0-9 aquaporin 1 (Colton blood group) Homo sapiens 45-56 12218304-1 2002 AIM: To determine whether glucose, NaCl and/or cholera toxin modify the expression of aquaporin-1 (AQP-1) water channel. Glucose 26-33 aquaporin 1 (Colton blood group) Homo sapiens 86-97 12218304-1 2002 AIM: To determine whether glucose, NaCl and/or cholera toxin modify the expression of aquaporin-1 (AQP-1) water channel. Glucose 26-33 aquaporin 1 (Colton blood group) Homo sapiens 99-104 12218304-3 2002 RESULTS: D-Glucose and NaCl (500 mosm/kg.H(2)O each) enhanced AQP-1 expression 2.4-fold (p < 0.05) and 4.0-fold (p < 0.01), respectively, which could be blocked 73 and 70% (p < 0.01), respectively, by cholera enterotoxin (10(-7) M). Glucose 9-18 aquaporin 1 (Colton blood group) Homo sapiens 62-67 12218304-7 2002 CONCLUSIONS: The increased urinary concentrating ability in proximal segment of the diabetic kidney associated with increased plasma glucose may be mediated via glucose"s ability to enhance AQP-1 expression, which leads to a more concentrated urine. Glucose 133-140 aquaporin 1 (Colton blood group) Homo sapiens 190-195 12218304-7 2002 CONCLUSIONS: The increased urinary concentrating ability in proximal segment of the diabetic kidney associated with increased plasma glucose may be mediated via glucose"s ability to enhance AQP-1 expression, which leads to a more concentrated urine. Glucose 161-168 aquaporin 1 (Colton blood group) Homo sapiens 190-195 11316863-0 2001 Expression of aquaporin-1 in human peritoneal mesothelial cells and its upregulation by glucose in vitro. Glucose 88-95 aquaporin 1 (Colton blood group) Homo sapiens 14-25 11316863-6 2001 More important, the expression of AQP1 in HPMC is not constitutive and the transcription and biosynthesis of AQP1 in HPMC is inducible by osmotic agents such as glucose and mannitol. Glucose 161-168 aquaporin 1 (Colton blood group) Homo sapiens 34-38 11316863-6 2001 More important, the expression of AQP1 in HPMC is not constitutive and the transcription and biosynthesis of AQP1 in HPMC is inducible by osmotic agents such as glucose and mannitol. Glucose 161-168 aquaporin 1 (Colton blood group) Homo sapiens 109-113 11316863-7 2001 There was significant enhancement of AQP1 biosynthesis upon exposure to glucose in a time- and dose-dependent manner (P < 0.0001). Glucose 72-79 aquaporin 1 (Colton blood group) Homo sapiens 37-41 11687943-4 2001 Furthermore, during glucose-induced osmosis during PD, nearly 40% of the total osmotic water flow occurs through molecular water channels, termed "aquaporin-1." Glucose 20-27 aquaporin 1 (Colton blood group) Homo sapiens 147-158 35438972-5 2022 Both membrane proteins, GLUT1 and aquaporin-1 (AQP1), on EM were shown to be key components for selective glucose detection by treatment with their inhibitors. Glucose 106-113 aquaporin 1 (Colton blood group) Homo sapiens 34-45 35438972-5 2022 Both membrane proteins, GLUT1 and aquaporin-1 (AQP1), on EM were shown to be key components for selective glucose detection by treatment with their inhibitors. Glucose 106-113 aquaporin 1 (Colton blood group) Homo sapiens 47-51