PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25063250-11	2014	In response to hypoxia stress and oxidative damage in ICP, the placenta activates HIF-1alpha and REDD1, which in turn may up-regulates glucose transport and anaerobic glycolysis.	Glucose	135-142	DNA damage inducible transcript 4	Homo sapiens	97-102	
26213322-9	2015	Of importance, RT-PCR and Western blotting demonstrated that high glucose inhibited DNA-damage-inducible transcript 4 (DDIT4) and TSC1/TSC2, up-regulated Rheb/mTOR/p70S6K and enhanced expression of the apoptosis regulating proteins, such as phospho-Bcl-2, cytochrome C and cleaved caspase.	Glucose	66-73	DNA damage inducible transcript 4	Homo sapiens	84-117	
26213322-9	2015	Of importance, RT-PCR and Western blotting demonstrated that high glucose inhibited DNA-damage-inducible transcript 4 (DDIT4) and TSC1/TSC2, up-regulated Rheb/mTOR/p70S6K and enhanced expression of the apoptosis regulating proteins, such as phospho-Bcl-2, cytochrome C and cleaved caspase.	Glucose	66-73	DNA damage inducible transcript 4	Homo sapiens	119-124	
29416624-3	2018	We investigated whether 1,25(OH)2D3 could inhibit the proliferation of rat mesangial cells exposed to high glucose via the DNA-damage-inducible transcript 4/mammalian target of rapamycin(DDIT4/mTOR) pathway.	Glucose	107-114	DNA damage inducible transcript 4	Homo sapiens	187-192	
25063250-12	2014	CONCLUSIONS: HIF-1alpha, REDD1 and mTOR may play a significant role in the reaction to hypoxia and oxidative stress and regulate glucose metabolism in the placenta of ICP patients.	Glucose	129-136	DNA damage inducible transcript 4	Homo sapiens	25-30	
33933315-12	2022	This study unexpectedly identified both KDM2B and DDIT4 as genes controlling BCG-driven re-methylation of histones, and the activation of the mTOR pathway for facilitated glucose transport respectively.	Glucose	171-178	DNA damage inducible transcript 4	Homo sapiens	50-55	
33933315-14	2022	The DDIT4 gene with known inhibitory role of mTOR was re-methylated after BCG, a step likely to allow improved glucose transport.	Glucose	111-118	DNA damage inducible transcript 4	Homo sapiens	4-9	
21460850-5	2011	Redd1 and TXNIP expression was induced by a synthetic glucose analog, 2-deoxyglucose (2-DG).	Glucose	54-61	DNA damage inducible transcript 4	Homo sapiens	0-5