PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35392573-11 2022 In cultured neurons, high glucose induced a high phosphorylated level of dynamin-related protein 1 (DRP1) and increased oxidative stress, resulting in cell apoptosis. Glucose 26-33 dynamin 1-like Mus musculus 73-98 34433037-5 2021 Mice carrying a homozygous Drp1 S600A knockin (Drp1 KI) mutation display larger mitochondria and enhanced lipid oxidation and respiratory capacities, granting improved glucose tolerance and thermogenic response upon high-fat feeding. Glucose 168-175 dynamin 1-like Mus musculus 27-31 34433037-5 2021 Mice carrying a homozygous Drp1 S600A knockin (Drp1 KI) mutation display larger mitochondria and enhanced lipid oxidation and respiratory capacities, granting improved glucose tolerance and thermogenic response upon high-fat feeding. Glucose 168-175 dynamin 1-like Mus musculus 47-51 35392573-11 2022 In cultured neurons, high glucose induced a high phosphorylated level of dynamin-related protein 1 (DRP1) and increased oxidative stress, resulting in cell apoptosis. Glucose 26-33 dynamin 1-like Mus musculus 100-104 32994406-9 2020 Finally, fragmented mitochondria and Drp1 mitochondrial translocation induced by high glucose were reduced following treatment with Mdivi1. Glucose 86-93 dynamin 1-like Mus musculus 37-41 28190775-0 2017 DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons. Glucose 27-34 dynamin 1-like Mus musculus 0-4 28190775-5 2017 Inducible deletion of DRP1 of mature POMC neurons (Drp1fl/fl-POMC-cre:ERT2) resulted in improved leptin sensitivity and glucose responsiveness. Glucose 120-127 dynamin 1-like Mus musculus 22-26 31063459-6 2019 Mechanistically, we showed that mitochondrial fission in high glucose conditions occurs through concomitant binding of phospho-Drp1S600 with mitochondrial fission factor (Mff) and actin-related protein 3 (Arp3), ultimately leading to accumulation of F-actin and Drp1 on the mitochondria. Glucose 62-69 dynamin 1-like Mus musculus 127-131 27597885-0 2016 Parkin Protects against Oxygen-Glucose Deprivation/Reperfusion Insult by Promoting Drp1 Degradation. Glucose 31-38 dynamin 1-like Mus musculus 83-87 26825530-6 2016 When isolated from diabetic mice and cultured in high glucose, Drp1-null podocytes had more elongated mitochondria and better mitochondrial fitness associated with enhanced oxygen consumption and ATP production than wild-type podocytes. Glucose 54-61 dynamin 1-like Mus musculus 63-67 24556414-10 2014 Importantly, inhibition of PKA or Drp1 significantly attenuates nitrite-induced mitochondrial respiration and glucose uptake. Glucose 110-117 dynamin 1-like Mus musculus 34-38