PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31448673-0 2020 CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis. Glucose 51-58 microtubule associated protein 1 light chain 3 beta Homo sapiens 12-16 31448673-4 2020 By inhibiting AMPK-MTOR-PIK3C3 pathway, high glucose suppresses the CAV-CAVIN-LC3B-mediated autophagic degradation of CAV1; therefore, more CAV1 is accumulated in the cytosol and utilized to form more caveolae in the cell membrane and facilitates the LDL transcytosis across endothelial cells. Glucose 45-52 microtubule associated protein 1 light chain 3 beta Homo sapiens 78-82 31448673-6 2020 Our results reveal that high glucose stimulates LDL transcytosis by a novel CAV1-CAVIN1-LC3B signaling-mediated autophagic degradation pathway. Glucose 29-36 microtubule associated protein 1 light chain 3 beta Homo sapiens 88-92 28580603-5 2017 In our results, high glucose significantly increased PTEN-induced putative kinase 1 (PINK1) and LC-3B expressions; as well it decreased cytochrome c oxidase subunit 4 expression and Mitotracker fluorescence intensity. Glucose 21-28 microtubule associated protein 1 light chain 3 beta Homo sapiens 96-101 24349516-7 2013 Furthermore, there were differential changes in levels of beclin-1, DRAM, and LC3B-II in response to changes in oxygen and glucose levels. Glucose 123-130 microtubule associated protein 1 light chain 3 beta Homo sapiens 78-82 35240195-3 2022 The expression levels of Sirt3, Foxo3a, PINK1, Parkin and LC3B in RPE subjected to high-glucose (HG, 30 mM D-glucose) conditions were detected by RT-PCR and western blotting. Glucose 88-95 microtubule associated protein 1 light chain 3 beta Homo sapiens 58-62 35240195-3 2022 The expression levels of Sirt3, Foxo3a, PINK1, Parkin and LC3B in RPE subjected to high-glucose (HG, 30 mM D-glucose) conditions were detected by RT-PCR and western blotting. Glucose 109-116 microtubule associated protein 1 light chain 3 beta Homo sapiens 58-62