PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28743992-3	2017	Here, we show that LPS induces endoplasmic reticulum (ER) stress and protein levels of P300, an acetyltransferase involved in glucose production.	Glucose	126-133	E1A binding protein p300	Mus musculus	87-91	
29273760-7	2017	Moreover, proliferation and ECM production in high glucose-challenged GMCs were attenuated by selective UTR antagonist, TRPC4 channel blocker, and CaMKII and CREB-binding protein/p300 inhibitors.	Glucose	51-58	E1A binding protein p300	Mus musculus	179-183	
29217654-5	2018	Mice lacking either p300 or CBP in islets developed glucose intolerance attributable to impaired insulin secretion, together with reduced alpha- and beta-cell area and islet insulin content.	Glucose	52-59	E1A binding protein p300	Mus musculus	20-24	
23625921-10	2013	Therefore, the results of the present study suggest that the glucose metabolite, ManNAc, induces switching from the inactive state by Ogt-Sirt1 to the active state by Mgea5, p300, and CBP at the Hcrt gene locus.	Glucose	61-68	E1A binding protein p300	Mus musculus	174-178	
26806835-7	2016	The involvement of histone acetylation in glucose-stimulated TXNIP expression was confirmed by reversing or enhancing acetylation using the histone acetyltransferase p300 inhibitor C646 or the histone deacetylase inhibitor trichostatin A.	Glucose	42-49	E1A binding protein p300	Mus musculus	166-170	
23804093-2	2013	Here we present a small-molecule (TTK21) activator of the histone acetyltransferases CBP/p300, which, when conjugated to glucose-based carbon nanosphere (CSP), passed the blood-brain barrier, induced no toxicity, and reached different parts of the brain.	Glucose	121-128	E1A binding protein p300	Mus musculus	89-93	
26718496-12	2016	These data indicate that glucose-induced EndMT in vivo and in vitro in the hearts of diabetic mice is possibly mediated by miR-200b and p300.	Glucose	25-32	E1A binding protein p300	Mus musculus	136-140	
25335984-12	2014	CONCLUSIONS: These data indicate glucose-induced EndMT in vitro and in vivo is possibly mediated through TGFbeta and regulated by miR-200b and p300.	Glucose	33-40	E1A binding protein p300	Mus musculus	143-147	
24379407-9	2014	In addition, inhibition of histone acetyltransferase activity of P300 significantly decreased hepatic Foxo1 mRNA and FOXO1 protein levels in fasted mice, as well as fasting blood glucose levels.	Glucose	179-186	E1A binding protein p300	Mus musculus	65-69	
22815486-5	2012	p300(G422S) and hepatic-deleted p300 mice exhibited significant lower blood glucose levels in the fasted and post-prandial states, indicating a role for p300 in maintaining basal HGP.	Glucose	76-83	E1A binding protein p300	Mus musculus	0-4	
22815486-5	2012	p300(G422S) and hepatic-deleted p300 mice exhibited significant lower blood glucose levels in the fasted and post-prandial states, indicating a role for p300 in maintaining basal HGP.	Glucose	76-83	E1A binding protein p300	Mus musculus	32-36	
22815486-5	2012	p300(G422S) and hepatic-deleted p300 mice exhibited significant lower blood glucose levels in the fasted and post-prandial states, indicating a role for p300 in maintaining basal HGP.	Glucose	76-83	E1A binding protein p300	Mus musculus	32-36	
21084751-6	2010	In cultured mouse hepatocytes, we showed that glucose-activated p300 acetylated ChREBP on Lys672 and increased its transcriptional activity by enhancing its recruitment to its target gene promoters.	Glucose	46-53	E1A binding protein p300	Mus musculus	64-68	
17065349-5	2006	High glucose induced fibronectin expression in the endothelial cells, which was associated with increased p300, PARP activity, and NF-kappaB activation.	Glucose	5-12	E1A binding protein p300	Mus musculus	106-110	
18842595-10	2008	Surprisingly, p300 down-regulation altered expression of other metabolic FXR target genes involved in lipoprotein and glucose metabolism, such that beneficial lipid and glucose profiles would be expected.	Glucose	118-125	E1A binding protein p300	Mus musculus	14-18	
18842595-10	2008	Surprisingly, p300 down-regulation altered expression of other metabolic FXR target genes involved in lipoprotein and glucose metabolism, such that beneficial lipid and glucose profiles would be expected.	Glucose	169-176	E1A binding protein p300	Mus musculus	14-18	
12665509-3	2003	Previous data demonstrate that the transcription factors Beta-2/NeuroD1 and Pdx-1, which are involved in glucose-stimulated insulin gene expression, interact with the histone acetylase p300, suggesting a role for histone acetylation in glucose regulation of the insulin gene expression.	Glucose	105-112	E1A binding protein p300	Mus musculus	185-189	
12665509-3	2003	Previous data demonstrate that the transcription factors Beta-2/NeuroD1 and Pdx-1, which are involved in glucose-stimulated insulin gene expression, interact with the histone acetylase p300, suggesting a role for histone acetylation in glucose regulation of the insulin gene expression.	Glucose	236-243	E1A binding protein p300	Mus musculus	185-189	
15496408-2	2004	Furthermore, we have shown that the glucose-mediated hyperacetylation of histone H4 depends on the recruitment of the histone acetyltransferase p300 by the beta cell-specific transcription factor Pdx-1.	Glucose	36-43	E1A binding protein p300	Mus musculus	144-148