PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35058510-5	2022	Targeted biopsies revealed that the tissues with labels 7-10 showed high expression levels of hypoxia-inducible factor 1-alpha, glucose transporter 3, and hexokinase 2, which are typical of IDH wild-type glioma, whereas those with labels 1 showed low expression of these proteins.	Glucose	128-135	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	190-193	
34075008-16	2021	CONCLUSION: Metabolic parameters of fluoro-deoxy-glucose PET/CT help in prognosticating IDH-1 wild-type GBM.	Glucose	49-56	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	88-93	
28569381-9	2017	Moreover, TP53TG1 and some tumor glucose metabolism related genes, such as GRP78, LDHA, and IDH1 were up-regulated significantly in U87 and LN18 cells under glucose deprivation.	Glucose	33-40	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	92-96	
30649892-4	2019	Hyperglycemia markedly upregulated the expression of glycolytic enzymes (glucokinase and 6-phosphofructo-1-kinase, PFK1) 5 h following glucose administration, while at 24 h posttreatment, it increased isocitrate dehydrogenase (IDH) activity, a key enzyme of the tricarboxylic acid cycle, and the expression of lipogenic factors (PGC1beta, Lpin1, and SREBP1).	Glucose	135-142	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	227-230	
29692895-12	2018	Conclusions: These results demonstrate that IDH1 mutant and IDH wildtype cells are easily distinguishable metabolically by analyzing expression profiles and glucose consumption.	Glucose	157-164	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	44-48	
29692895-12	2018	Conclusions: These results demonstrate that IDH1 mutant and IDH wildtype cells are easily distinguishable metabolically by analyzing expression profiles and glucose consumption.	Glucose	157-164	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	44-47	
30720071-3	2019	The results demonstrated that mutation of IDH1 exacerbated the effects of OA and PA on cell viability and apoptosis, and consistently elevated the production of reactive oxygen species in HCT116 cells, particularly in the absence of glucose.	Glucose	233-240	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	42-46	
30720071-4	2019	Furthermore, mutation of IDH1 inhibited the rate of fatty acid oxidation (FAO), but elevated the glucose consumption in HCT116 cells.	Glucose	97-104	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	25-29	
26045167-6	2015	(13)C-MRS also revealed a reduction in glucose flux to glutamate in IDH1 mutant cells.	Glucose	39-46	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	68-72	
28564604-4	2017	On a molecular level, diminished IDH1 activity results in reduced alpha-ketoglutarate (alphaKG) and NADPH production, paralleled by deficient carbon flux from glucose or acetate into lipids, exhaustion of reduced glutathione, increased levels of reactive oxygen species (ROS), and enhanced histone methylation and differentiation marker expression.	Glucose	159-166	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	33-37	
27856334-8	2017	We also observed an unusual lipogenic pathway in which carbon from glucose supplies mitochondrial production of alpha-ketoglutarate (AKG), which is then trafficked to the cytosol and used to supply reductive carboxylation by isocitrate dehydrogenase 1 (IDH1).	Glucose	67-74	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	225-251	
27856334-8	2017	We also observed an unusual lipogenic pathway in which carbon from glucose supplies mitochondrial production of alpha-ketoglutarate (AKG), which is then trafficked to the cytosol and used to supply reductive carboxylation by isocitrate dehydrogenase 1 (IDH1).	Glucose	67-74	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	253-257	
27856334-10	2017	In CTP deficient cells, IDH1 inhibition suppresses lipogenesis from either glucose or glutamine, implicating IDH1 as a required component of fatty acid synthesis in states of CTP deficiency.	Glucose	75-82	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	24-28	
23064941-2	2013	A mutation in isocitrate dehydrogenase 1 (IDH1), the enzyme involved in lipid metabolism and glucose sensing, has been identified in a variety of diffuse gliomas.	Glucose	93-100	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	14-40	
23064941-2	2013	A mutation in isocitrate dehydrogenase 1 (IDH1), the enzyme involved in lipid metabolism and glucose sensing, has been identified in a variety of diffuse gliomas.	Glucose	93-100	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	42-46