PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18204471-8	2008	Thrombin-promoted nucleotide release was inhibited by BAPTA-AM, brefeldin A and cytochalasin D, and was insensitive to Pertussis toxin and PI3-kinase inhibitors.	Cytochalasin D	80-94	coagulation factor II, thrombin	Homo sapiens	0-8	
9684857-3	1998	The inhibitory effect of thrombin required actin polymerisation and was not observed when interaction of CD38 with the cytoskeleton was prevented by cytochalasin D.	Cytochalasin D	149-163	coagulation factor II, thrombin	Homo sapiens	25-33	
16300929-7	2006	Inhibition of actin polymerization by cytochalasin D inhibits translocation and activation of both caspases, suggesting that thrombin stimulates caspase 3 and 9 activation and association with the reorganizing actin cytoskeleton.	Cytochalasin D	38-52	coagulation factor II, thrombin	Homo sapiens	125-133	
16702038-2	2006	We have previously reported that cytochalasin D (Cyt D) inhibits thapsigargin-evoked store-operated Ca(2+) entry (SOCE), which is believed to contribute a major component of thrombin-evoked Ca(2+) entry in platelets.	Cytochalasin D	33-47	coagulation factor II, thrombin	Homo sapiens	174-182	
15557012-7	2005	Posttreatment with cytochalasin D abolished thrombin-induced cell stiffening.	Cytochalasin D	19-33	coagulation factor II, thrombin	Homo sapiens	44-52	
10682859-1	2000	Pretreatment of intact platelets with cytochalasin D prevented actin polymerization and cytoskeleton reorganization induced by thrombin, but did not affect platelet aggregation.	Cytochalasin D	38-52	coagulation factor II, thrombin	Homo sapiens	127-135	
8223720-4	1993	Cytochalasin D, known to inhibit the increase in F-actin after thrombin, also inhibits the fall in T beta 4-actin complex and the increase in nucleation sites.	Cytochalasin D	0-14	coagulation factor II, thrombin	Homo sapiens	63-71	
8704107-9	1996	Cytochalasin D blocked the ability of thrombin to restore focal adhesions and phosphorylate p125FAK.	Cytochalasin D	0-14	coagulation factor II, thrombin	Homo sapiens	38-46	
7512933-2	1994	Translocation of the enzyme became maximal within 1-2 min of thrombin stimulation and was suppressed by cytochalasin D or upon inhibition of aggregation.	Cytochalasin D	104-118	coagulation factor II, thrombin	Homo sapiens	61-69	
1385445-7	1992	The induction of tyrosine phosphorylation of pp125FAK was inhibited in thrombin- and collagen-treated platelets preincubated with cytochalasin D, which prevents actin polymerization following activation.	Cytochalasin D	130-144	coagulation factor II, thrombin	Homo sapiens	71-79	
7088173-0	1982	Effect of cytochalasin D on thrombin-induced actin filaments in platelets.	Cytochalasin D	10-24	coagulation factor II, thrombin	Homo sapiens	28-36