PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27721022-0	2017	Synergistic induction of CTGF by cytochalasin D and TGFbeta-1 in primary human renal epithelial cells: Role of transcriptional regulators MKL1, YAP/TAZ and Smad2/3.	Cytochalasin D	33-47	cellular communication network factor 2	Homo sapiens	25-29	
11518778-7	2001	Inhibition of RhoA depolymerized the actin cytoskeleton, as did treatment with cytochalasin D. Preincubation of the human renal fibroblasts with cytochalasin D prevented induction of CTGF by LPA, indicating a strong contribution of an intact cytoskeleton.	Cytochalasin D	79-93	cellular communication network factor 2	Homo sapiens	183-187	
12951326-9	2003	Given the fact that cytochalasin D sequesters G-actin, a decrease in G-actin increased CTGF, while increased levels of G-actin corresponded to reduced CTGF expression.	Cytochalasin D	20-34	cellular communication network factor 2	Homo sapiens	87-91	
12951326-9	2003	Given the fact that cytochalasin D sequesters G-actin, a decrease in G-actin increased CTGF, while increased levels of G-actin corresponded to reduced CTGF expression.	Cytochalasin D	20-34	cellular communication network factor 2	Homo sapiens	151-155	
18760941-4	2009	RESULTS: Here we demonstrate that several CTGF/Cyr61/Nov (CCN) family members are differentially affected by either inhibition of actin polymerization (cytochalasin D treatment), promotion of actin polymerization (jasplakinolide treatment), inhibition of RhoA/rho kinase (ROCK) signaling (Y27632 treatment) and Rac1 signaling.	Cytochalasin D	152-166	cellular communication network factor 2	Homo sapiens	42-46	
18760941-5	2009	We also show that the Smad site in the CTGF/CCN2 promoter is responsive to both Rac1 inhibition and cytochalasin D treatment, suggesting a role of TGFbeta/Smad signaling in mediating the effects of actin dynamics and Rac1.	Cytochalasin D	100-114	cellular communication network factor 2	Homo sapiens	39-43	
18760941-5	2009	We also show that the Smad site in the CTGF/CCN2 promoter is responsive to both Rac1 inhibition and cytochalasin D treatment, suggesting a role of TGFbeta/Smad signaling in mediating the effects of actin dynamics and Rac1.	Cytochalasin D	100-114	cellular communication network factor 2	Homo sapiens	44-48	
16707113-11	2006	The phenotypic changes resembled changes observed after treatment of the cells with cytochalasin D, which has been shown to interfere with CTGF induction.	Cytochalasin D	84-98	cellular communication network factor 2	Homo sapiens	139-143