PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12433826-0 2002 Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities. Olopatadine Hydrochloride 11-22 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 87-91 12433826-4 2002 We identified the enzymes catalyzing olopatadine metabolism and investigated the effect of olopatadine on human p450 activities. Olopatadine Hydrochloride 91-102 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 112-116 12433826-7 2002 Incubation of olopatadine with cDNA-expressed human p450 isozymes confirmed that M1 formation was almost exclusively catalyzed by CYP3A4. Olopatadine Hydrochloride 14-25 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 52-56 12433826-10 2002 Olopatadine did not inhibit p450 activities when it was simultaneously incubated with substrates for different p450 isozymes. Olopatadine Hydrochloride 0-11 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 111-115