PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --> TC.Cbl.OH(2) + CN(-)/N(3)(-).	Cyanides	167-174	Cbl proto-oncogene	Homo sapiens	153-156	
11578192-3	2001	The formation constants K(CN) for the 1:1 cyanide adducts (R(CN)Cbl) were found to be 0.38 +/- 0.03, 0.43 +/- 0.03, and 123 +/- 9 M(-1) for R = Me, CH(2)Br, and CF(3), respectively.	Cyanides	42-49	Cbl proto-oncogene	Homo sapiens	64-67	
11154562-2	2000	Under these conditions rate-determining Co-C heterolytic cleavage is preceded by rapid addition of cyanide to AdoCbl to form an intermediate, (beta-5"-deoxyadenosyl)(alpha-cyano)cobalamin ((beta-Ado)(alpha-CN)Cbl-), identified by 1H NMR spectroscopy.	Cyanides	99-106	Cbl proto-oncogene	Homo sapiens	113-116	
11154562-7	2000	A mechanism in 92% DMF/8% D2O is proposed which involves rapid reversible formation of (beta-Ado)(alpha-CN)Cbl- from base-off AdoCbl plus cyanide, followed by rate-determining solvent-assisted cleavage of the Co-C bond of the intermediate and subsequent rapid addition of a second cyanide to give the products.	Cyanides	138-145	Cbl proto-oncogene	Homo sapiens	107-110	
11154562-7	2000	A mechanism in 92% DMF/8% D2O is proposed which involves rapid reversible formation of (beta-Ado)(alpha-CN)Cbl- from base-off AdoCbl plus cyanide, followed by rate-determining solvent-assisted cleavage of the Co-C bond of the intermediate and subsequent rapid addition of a second cyanide to give the products.	Cyanides	281-288	Cbl proto-oncogene	Homo sapiens	107-110	
15702190-1	2005	Ligand substitution reactions of the vitamin B12 analog cyanoimidazolylcobamide, CN(Im)Cbl, with cyanide were studied.	Cyanides	97-104	Cbl proto-oncogene	Homo sapiens	87-90	
12553836-7	2003	At low pH and total NP concentration (pH < 3, [NP]/[Cbl(II)] approximately 1), the cyano-bridged successor complex [Cbl(III)-(mu-NC)-Fe(I)(CN)(3)(NO(+))](-) (1(s)()) is the final reaction product formed in an inner-sphere electron transfer reaction that is coupled to the release of cyanide from coordinated nitroprusside.	Cyanides	286-293	Cbl proto-oncogene	Homo sapiens	119-122	
12553836-8	2003	At higher pH, subsequent reactions were observed which involve the attack of cyanide released in the electron transfer step on the initially formed cyano-bridged species, and lead to the formation of Cbl(III)CN and [Fe(I)(CN)(4)(NO(+))](2)(-).	Cyanides	77-84	Cbl proto-oncogene	Homo sapiens	200-203	
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --> TC.Cbl.OH(2) + CN(-)/N(3)(-).	Cyanides	167-174	Cbl proto-oncogene	Homo sapiens	213-216	
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --> TC.Cbl.OH(2) + CN(-)/N(3)(-).	Cyanides	167-174	Cbl proto-oncogene	Homo sapiens	213-216	
7019262-3	1981	The natural forms of serum Cbl were converted to cyanocobalamin (CN Cbl) by this process of extraction which included cyanide (CN).	Cyanides	118-125	Cbl proto-oncogene	Homo sapiens	27-30	
7019262-3	1981	The natural forms of serum Cbl were converted to cyanocobalamin (CN Cbl) by this process of extraction which included cyanide (CN).	Cyanides	118-125	Cbl proto-oncogene	Homo sapiens	68-71	
7019262-3	1981	The natural forms of serum Cbl were converted to cyanocobalamin (CN Cbl) by this process of extraction which included cyanide (CN).	Cyanides	65-67	Cbl proto-oncogene	Homo sapiens	27-30	
7019262-3	1981	The natural forms of serum Cbl were converted to cyanocobalamin (CN Cbl) by this process of extraction which included cyanide (CN).	Cyanides	65-67	Cbl proto-oncogene	Homo sapiens	68-71