PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18789379-5	2008	The activity of hepatic drug-metabolizing enzymes and expression of hepatic cytochrome P450 (CYP) 1A2, CYP3A2 and CYP2D1, which oxidize DZN to DZN-oxon, a potent ChE inhibitor, were measured before DZN injection.	Diazinon	136-139	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	103-109	
18789379-5	2008	The activity of hepatic drug-metabolizing enzymes and expression of hepatic cytochrome P450 (CYP) 1A2, CYP3A2 and CYP2D1, which oxidize DZN to DZN-oxon, a potent ChE inhibitor, were measured before DZN injection.	Diazinon	143-146	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	103-109	
9890448-5	1999	Results indicate that, after diazinon preincubation, CYP3A2-catalyzed reactions (2beta- and 6beta-testosterone hydroxylation) are very efficiently inhibited; CYP2C11- and CYP2B1/2-catalyzed reactions (2alpha- and 16beta-testosterone hydroxylation, respectively) are weakly inhibited, while CYP2E1-, CYP2A1/2-, and CYP1A1/2-related activities were unaffected.	Diazinon	29-37	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	53-59	
9890448-6	1999	Results obtained by using chemical inhibitors or antibodies selectively active against specific CYPs provide a direct evidence for the involvement of CYP2C11, CYP3A2, and CYP2B1/2, indicating that each of them contributed about 40-50% of the diazinon metabolism, in hepatic microsomes from untreated, phenobarbital-, and dexamethasone-treated rats, respectively.	Diazinon	242-250	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	159-165