PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14764912-5 2004 Commensurate with this antioxidant effect, 100 microM betaC also protected hepatocytes against both glycochenodeoxycholic acid-induced cellular necrosis and apoptosis, which was associated with reduction in caspase 3 activation, inhibition of mitochondrial cytochrome c release in rat hepatocytes, and prevention of the mitochondrial permeability transition in both liver mitochondria and rat hepatocytes. beta Carotene 54-59 caspase 3 Rattus norvegicus 207-216 12448825-4 2002 Effect of antioxidants on the activation of caspase-3 was determined by feeding a group of diabetic rats diet supplemented with a comprehensive mixture of antioxidants, including Trolox, alpha-tocopherol, N-acetyl cysteine, ascorbic acid, beta-carotene and selenium for 2-14 months, and also under in vitro conditions by incubating isolated retinal capillary cells with antioxidants with wide range of actions. beta Carotene 239-252 caspase 3 Rattus norvegicus 44-53 19957244-7 2010 1 muM beta-carotene decreased oxidative stress and prevented ethanol-induced cell death by inhibiting caspase-9 and caspase-3 expression. beta Carotene 6-19 caspase 3 Rattus norvegicus 116-125