PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18819794-0 2008 Itk kinase inhibitors: initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead. benzimidazole 105-118 IL2 inducible T cell kinase Homo sapiens 0-3 18819794-1 2008 Previously, we reported a series of novel benzimidazole based Itk inhibitors that exhibited excellent enzymatic potency and selectivity but low microsomal stability. benzimidazole 42-55 IL2 inducible T cell kinase Homo sapiens 62-65 18819799-1 2008 A series of novel potent benzimidazole based inhibitors of interleukin-2 T-cell kinase (Itk) were prepared. benzimidazole 25-38 IL2 inducible T cell kinase Homo sapiens 59-86 18819799-1 2008 A series of novel potent benzimidazole based inhibitors of interleukin-2 T-cell kinase (Itk) were prepared. benzimidazole 25-38 IL2 inducible T cell kinase Homo sapiens 88-91 17499505-0 2007 Hit-to-lead studies on benzimidazole inhibitors of ITK: discovery of a novel class of kinase inhibitors. benzimidazole 23-36 IL2 inducible T cell kinase Homo sapiens 51-54