PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26976506-1 2016 For finding the novel inhibitor of nuclear factor kappaB activity, a series of benzimidazole derivatives were rationally designed, synthesized and systematically studied for their in vitro activities against LPS induced NF-kappaB inhibition in RAW 264.7 cells using the SEAP assay based on the flexible chalcone JSH ((E)-1-(2-hydroxy-6-(isopentyloxy)phenyl)-3-(4-hydroxy phenyl)prop-2-en-1-one) which was previously reported. benzimidazole 79-92 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 220-229