PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24045148-3 2013 Compound III is a benzoimidazole, which has a submicromolar IC50 in both human and rat recombinant mPGES-1. benzimidazole 18-32 prostaglandin E synthase Mus musculus 99-106 29597170-3 2018 C (5)-substitution of the benzimidazole ring of BRP-7 by carboxylic acid and its bioisosteres provided compounds, exemplified by 57 that potently suppress LT formation (IC50 = 0.05 muM) by targeting FLAP along with inhibition of mPGES-1 (IC50 = 0.42 muM). benzimidazole 26-39 prostaglandin E synthase Mus musculus 229-236 35152061-0 2022 Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase. benzimidazole 13-26 prostaglandin E synthase Mus musculus 73-80