PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21798739-0	2011	Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARgamma partial agonist.	benzimidazole	53-66	peroxisome proliferator activated receptor gamma	Homo sapiens	67-76	
22357520-2	2012	To understand how telmisartan partially activates PPARgamma, we determined the ternary complex structure of PPARgamma, telmisartan, and a coactivator peptide from steroid receptor coactivator-1 at a resolution of 2.18 A. Crystallographic analysis revealed that telmisartan exhibits an unexpected binding mode in which the central benzimidazole ring is engaged in a non-canonical--and suboptimal--hydrogen-bonding network around helix 12 (H12).	benzimidazole	330-343	peroxisome proliferator activated receptor gamma	Homo sapiens	108-117	
32298535-4	2020	Inspired by the  pharmacodynamics of HYL-6d and the selective PPARgamma ligand VSP-51, the benzimidazole was replaced by a carbazole or an indole core .	benzimidazole	91-104	peroxisome proliferator activated receptor gamma	Homo sapiens	62-71	
27602589-4	2017	The central benzimidazole ring, however, remained intact considering its great affinity toward AT1R and PPARgamma.	benzimidazole	12-25	peroxisome proliferator activated receptor gamma	Homo sapiens	104-113	
21798739-2	2011	A novel benzimidazole series of centrally penetrant PPARgamma partial agonists has been identified.	benzimidazole	8-21	peroxisome proliferator activated receptor gamma	Homo sapiens	52-61	
20073471-2	2010	On the basis of these findings and docking pose similarity between telmisartan and rosiglitazone in PPAR gamma active site, two classes of benzimidazole derivatives were designed and synthesized as dual PPAR gamma agonist/angiotensin II antagonists for the possible treatment of metabolic syndrome.	benzimidazole	139-152	peroxisome proliferator activated receptor gamma	Homo sapiens	100-110	
20073471-2	2010	On the basis of these findings and docking pose similarity between telmisartan and rosiglitazone in PPAR gamma active site, two classes of benzimidazole derivatives were designed and synthesized as dual PPAR gamma agonist/angiotensin II antagonists for the possible treatment of metabolic syndrome.	benzimidazole	139-152	peroxisome proliferator activated receptor gamma	Homo sapiens	203-213