PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30371063-7	2018	Furthermore, several representative privileged substructures that are essential for FXR binders, such as benzimidazole, indole, and stilbene moiety, were detected using information gain and substructure frequency analysis.	benzimidazole	105-118	nuclear receptor subfamily 1 group H member 4	Homo sapiens	84-87	
25072161-0	2014	Pharmacophore modeling, 3D-QSAR and molecular docking studies of benzimidazole derivatives as potential FXR agonists.	benzimidazole	65-78	nuclear receptor subfamily 1 group H member 4	Homo sapiens	104-107	
25072161-2	2014	Atom-based three-dimensional quantitative structure activity relationship (3D-QSAR) models were developed for a series of 48 benzimidazole-based agonists of FXR.	benzimidazole	125-138	nuclear receptor subfamily 1 group H member 4	Homo sapiens	157-160	
25072161-6	2014	Furthermore, molecular docking simulation was performed to understand the binding affinity of 48 benzimidazole-based compounds against the active site of human FXR protein.	benzimidazole	97-110	nuclear receptor subfamily 1 group H member 4	Homo sapiens	160-163	
25072161-9	2014	Substitution effects at different positions of benzimidazole derivatives would lead to the discovery of new agonists against human FXR protein.	benzimidazole	47-60	nuclear receptor subfamily 1 group H member 4	Homo sapiens	131-134	
28190654-0	2017	Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists.	benzimidazole	30-43	nuclear receptor subfamily 1 group H member 4	Homo sapiens	102-105	
28190654-1	2017	We describe here a novel chemotype with substituted benzimidazole scaffold for nonsteroidal farnesoid X receptor (FXR) antagonists starting from the identification of a screening hit, BB-4.	benzimidazole	52-65	nuclear receptor subfamily 1 group H member 4	Homo sapiens	114-117