PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30862488-0 2019 Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancer. benzimidazole 28-41 KRAS proto-oncogene, GTPase Homo sapiens 88-92 30862488-6 2019 The screening identified the cytotoxic effects of benzimidazole derivatives on KRAS-mutant lung cancer cells. benzimidazole 50-63 KRAS proto-oncogene, GTPase Homo sapiens 79-83 30862488-7 2019 Treatments with two benzimidazole derivatives, methiazole and fenbendazole-both of which are structurally specific-yielded significant suppression of the RAS-related signaling pathways in KRAS-mutated cells. benzimidazole 20-33 KRAS proto-oncogene, GTPase Homo sapiens 188-192 30862488-9 2019 Our study demonstrates that these benzimidazole derivatives play an important role in suppressing KRAS-mutant lung cancer cells, thus offering a novel combinatorial therapeutic approach against such cancer cells. benzimidazole 34-47 KRAS proto-oncogene, GTPase Homo sapiens 98-102