PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19888760-0	2009	Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents.	benzimidazole	67-80	poly (ADP-ribose) polymerase family, member 1	Mus musculus	87-116	
19888760-0	2009	Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents.	benzimidazole	67-80	poly (ADP-ribose) polymerase family, member 1	Mus musculus	118-124	
19888760-2	2009	As one of the strategies to expand our portfolio of PARP-1 inhibitors, we pursued unsaturated heterocycles to replace the saturated cyclic amine derivatives appended to the benzimidazole core.	benzimidazole	173-186	poly (ADP-ribose) polymerase family, member 1	Mus musculus	52-58	
18541433-1	2008	We have developed a series of cyclic amine-containing benzimidazole carboxamide poly(ADP-ribose)polymerase (PARP) inhibitors, with good PARP-1 enzyme potency, as well as cellular potency.	benzimidazole	54-67	poly (ADP-ribose) polymerase family, member 1	Mus musculus	80-106	
18541433-1	2008	We have developed a series of cyclic amine-containing benzimidazole carboxamide poly(ADP-ribose)polymerase (PARP) inhibitors, with good PARP-1 enzyme potency, as well as cellular potency.	benzimidazole	54-67	poly (ADP-ribose) polymerase family, member 1	Mus musculus	108-112	
18541433-1	2008	We have developed a series of cyclic amine-containing benzimidazole carboxamide poly(ADP-ribose)polymerase (PARP) inhibitors, with good PARP-1 enzyme potency, as well as cellular potency.	benzimidazole	54-67	poly (ADP-ribose) polymerase family, member 1	Mus musculus	136-142	
18586490-0	2008	Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent.	benzimidazole	59-72	poly (ADP-ribose) polymerase family, member 1	Mus musculus	87-114	
18586490-0	2008	Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent.	benzimidazole	59-72	poly (ADP-ribose) polymerase family, member 1	Mus musculus	116-120	
18586490-3	2008	Utilizing a benzimidazole carboxamide scaffold in which the amide forms a key intramolecular hydrogen bond for optimal interaction with the enzyme, we have identified a novel series of PARP inhibitors containing a quaternary methylene-amino substituent at the C-2 position of the benzimidazole.	benzimidazole	12-25	poly (ADP-ribose) polymerase family, member 1	Mus musculus	185-189