PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24448802-8 2014 The macrolide antibiotic bafilomycin A1 inhibited CS-induced Ca(2+) release and prevented CFTR clearance from the plasma membrane, further linking cytoplasmic Ca(2+) and CFTR internalization. Macrolides 4-13 CF transmembrane conductance regulator Homo sapiens 90-94 24448802-8 2014 The macrolide antibiotic bafilomycin A1 inhibited CS-induced Ca(2+) release and prevented CFTR clearance from the plasma membrane, further linking cytoplasmic Ca(2+) and CFTR internalization. Macrolides 4-13 CF transmembrane conductance regulator Homo sapiens 170-174 11233797-5 2001 Also, a link has been suggested between the macrolide transmembrane carrier system and the P-glycoprotein family, which comprises MDR (multiple drug resistance) and CFTR (cystic fibrosis transmembrane conductance regulator), which are respectively involved in the chemotherapeutic resistance of cancer cells and in the genesis of cystic fibrosis. Macrolides 44-53 CF transmembrane conductance regulator Homo sapiens 165-169 16167517-1 2005 Macrolides are accumulated in phagocytes, partially via an active transport system; the membrane carrier is not identified but many data indicate a link with the P-glycoprotein family which includes the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Macrolides 0-10 CF transmembrane conductance regulator Homo sapiens 203-254 16167517-1 2005 Macrolides are accumulated in phagocytes, partially via an active transport system; the membrane carrier is not identified but many data indicate a link with the P-glycoprotein family which includes the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Macrolides 0-10 CF transmembrane conductance regulator Homo sapiens 256-260 16167517-7 2005 These data suggest that the macrolide carriers (for entry and efflux) are not strictly specific for phagocytes and that the CFTR protein plays a role in macrolide uptake. Macrolides 28-37 CF transmembrane conductance regulator Homo sapiens 124-128 16167517-7 2005 These data suggest that the macrolide carriers (for entry and efflux) are not strictly specific for phagocytes and that the CFTR protein plays a role in macrolide uptake. Macrolides 153-162 CF transmembrane conductance regulator Homo sapiens 124-128 11233797-5 2001 Also, a link has been suggested between the macrolide transmembrane carrier system and the P-glycoprotein family, which comprises MDR (multiple drug resistance) and CFTR (cystic fibrosis transmembrane conductance regulator), which are respectively involved in the chemotherapeutic resistance of cancer cells and in the genesis of cystic fibrosis. Macrolides 44-53 CF transmembrane conductance regulator Homo sapiens 171-222