PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29676014-5	2018	In addition, the successful use of macrolide antibiotics to treat lung infections in these conditions further confirms that the innate immune system is the key conductor of inflammation in these pulmonary diseases, as there is a strong body of evidence that macrolides are able to modulate the NLRP3 inflammasome and interleukin-1beta and interleukin-18 secretion, both of which are central players in the innate immune response.	Macrolides	35-44	interleukin 18	Homo sapiens	339-353	
29676014-5	2018	In addition, the successful use of macrolide antibiotics to treat lung infections in these conditions further confirms that the innate immune system is the key conductor of inflammation in these pulmonary diseases, as there is a strong body of evidence that macrolides are able to modulate the NLRP3 inflammasome and interleukin-1beta and interleukin-18 secretion, both of which are central players in the innate immune response.	Macrolides	258-268	interleukin 18	Homo sapiens	339-353