PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8640957-2 1996 The oxidation effect of methylglyoxal significantly potentiated by thrombin, depends on both the ketoaldehyde and the agonist concentrations. Pyruvaldehyde 24-37 coagulation factor II, thrombin Homo sapiens 67-75 8640957-6 1996 Methylglyoxal inhibits platelet aggregation induced by several agonists and ATP release induced by thrombin. Pyruvaldehyde 0-13 coagulation factor II, thrombin Homo sapiens 99-107 8288025-8 1993 A further significant increase was observed in platelets stimulated with thrombin in the presence of methylglyoxal. Pyruvaldehyde 101-114 coagulation factor II, thrombin Homo sapiens 73-81 25307422-5 2014 METHODS: MGO-mediated ATIII inhibition was confirmed using inverse experiments detecting activity of the ATIII targets thrombin and factor Xa. Pyruvaldehyde 9-12 coagulation factor II, thrombin Homo sapiens 119-127 25307422-8 2014 RESULTS AND CONCLUSIONS: MGO concentration-dependently attenuated inhibition of thrombin and factor Xa by ATIII in PBS-based assays, both in the presence and absence of heparin. Pyruvaldehyde 25-28 coagulation factor II, thrombin Homo sapiens 80-88