PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19375802-9	2009	Hence, concluded that methylglyoxal augmented the IL-6 and IL-1 beta, expression of TLR 4 and TLR 9 and produced MAPKs, important regulators of ROIs and RNIs.	Pyruvaldehyde	22-35	interleukin 1 beta	Mus musculus	59-68	
25243815-4	2014	In vivo, CE administration for 16 wk significantly ameliorated renal dysfunction in type 2 diabetic db/db mice, partially due to MG trapping, which in turn inhibited AGEs formation and lowered proinflammatory cytokines, including tumor necrosis factor alpha and IL-1beta.	Pyruvaldehyde	129-131	interleukin 1 beta	Mus musculus	262-270	
10752532-4	2000	Exposure of HPMC to acetaldehyde, formaldehyde, glyoxal, methylglyoxal, furaldehyde, but not to 5-hydroxymethyl-furfural, resulted in dose-dependent inhibition of cell growth, viability, and interleukin-1beta (IL-1beta)-stimulated IL-6 release; for several GDP, this suppression was significantly greater compared with L929 cells.	Pyruvaldehyde	57-70	interleukin 1 beta	Mus musculus	191-208	
10752532-4	2000	Exposure of HPMC to acetaldehyde, formaldehyde, glyoxal, methylglyoxal, furaldehyde, but not to 5-hydroxymethyl-furfural, resulted in dose-dependent inhibition of cell growth, viability, and interleukin-1beta (IL-1beta)-stimulated IL-6 release; for several GDP, this suppression was significantly greater compared with L929 cells.	Pyruvaldehyde	57-70	interleukin 1 beta	Mus musculus	210-218	
31557885-7	2019	MGO treatment increased mRNA expression of inflammation-related molecules, interleukin (IL)-1beta, IL-6, and toll-like receptor 4 (TLR4).	Pyruvaldehyde	0-3	interleukin 1 beta	Mus musculus	75-97	
31370192-6	2019	Interestingly, administering LB in MGO-treated cells and mice upregulated the expression of Nrf2 and Glo1, and downregulated the expression of IL-1beta and TNF-alpha.	Pyruvaldehyde	35-38	interleukin 1 beta	Mus musculus	143-151