PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26900946-4	2016	AAE3 has been proposed to catalyze the first step in an alternative pathway of oxalate degradation.	Oxalates	79-86	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	0-4	
28039904-2	2017	The gene AAE3 was recently identified to encode an oxalyl-CoA synthetase (OCS) in Arabidopsis that catalyses the conversion of oxalate and CoA into oxalyl-CoA.	Oxalates	127-134	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	9-13	
26900946-6	2016	Here, we identify the Medicago truncatula AAE3 (MtAAE3) and show that it encodes an oxalyl-CoA synthetase activity exhibiting high activity against oxalate with a Km = 81 +- 9 muM and Vmax = 19 +- 0.9 mumoles min-1mg protein-1.	Oxalates	148-155	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	42-46	
26900946-10	2016	Taken together, these results suggest that AAE3 dependent turnover of oxalate is important to different plants and functions in the regulation of tissue calcium oxalate crystal accumulation and in defense against oxalate-secreting phytopathogens.	Oxalates	70-77	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	43-47	
26900946-10	2016	Taken together, these results suggest that AAE3 dependent turnover of oxalate is important to different plants and functions in the regulation of tissue calcium oxalate crystal accumulation and in defense against oxalate-secreting phytopathogens.	Oxalates	161-168	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	43-47	
22447686-5	2012	Recombinant AAE3 protein has high activity against oxalate, with K(m) = 149.0 +- 12.7 muM and V(max) = 11.4 +- 1.0 mumol/min/mg protein, but no detectable activity against other organic acids tested.	Oxalates	51-58	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	12-16	
22447686-6	2012	Allelic aae3 mutants lacked oxalyl-CoA synthetase activity and were unable to degrade oxalate into CO(2).	Oxalates	86-93	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	8-12	
22447686-10	2012	Our results demonstrate that, in Arabidopsis, oxalyl-CoA synthetase encoded by AAE3 is required for oxalate degradation, for normal seed development, and for defense against an oxalate-producing fungal pathogen.	Oxalates	100-107	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	79-83	
22447686-10	2012	Our results demonstrate that, in Arabidopsis, oxalyl-CoA synthetase encoded by AAE3 is required for oxalate degradation, for normal seed development, and for defense against an oxalate-producing fungal pathogen.	Oxalates	177-184	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	79-83