PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6630519-3 1983 To investigate the mechanism of its cholesterol-lowering action, we studied the effects of DCA and its hepatic metabolites, glyoxylate and oxalate, on the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoA reductase) obtained from livers of healthy, reverse light-cycled rats. Oxalates 139-146 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 167-233