PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24597142-4	2014	The innovation in antilithiatic proteins is that they are anionic, rich in acidic amino acids which make oxalate unavailable by interacting with calcium and have EF Hand domain which is a characteristic feature of various calcium binding protein like calgranulin, osteopontin.	Oxalates	105-112	secreted phosphoprotein 1	Homo sapiens	264-275	
22466558-5	2012	Reverse transcription polymerase chain reaction (RT-PCR) analysis revealed that gallotannin significantly attenuated oxalate-induced mRNA and protein expressions of monocyte chemoattractant protein 1 (MCP-1), osteopontin (OPN), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase subunit p22(phox) and p47(phox) in human primary renal epithelial cells (HRCs).	Oxalates	117-124	secreted phosphoprotein 1	Homo sapiens	209-220	
21932131-4	2012	[(14)C]-oxalate-labelled COD crystals with intracrystalline (IC), surface-bound (SB) and IC + SB OPN, were generated from ultrafiltered (UF) urine containing 0, 1 and 5 mg/L human milk OPN and incubated with MDCKII cells, using UF urine as the binding medium.	Oxalates	8-15	secreted phosphoprotein 1	Homo sapiens	97-100	
21932131-4	2012	[(14)C]-oxalate-labelled COD crystals with intracrystalline (IC), surface-bound (SB) and IC + SB OPN, were generated from ultrafiltered (UF) urine containing 0, 1 and 5 mg/L human milk OPN and incubated with MDCKII cells, using UF urine as the binding medium.	Oxalates	8-15	secreted phosphoprotein 1	Homo sapiens	185-188	
22466558-5	2012	Reverse transcription polymerase chain reaction (RT-PCR) analysis revealed that gallotannin significantly attenuated oxalate-induced mRNA and protein expressions of monocyte chemoattractant protein 1 (MCP-1), osteopontin (OPN), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase subunit p22(phox) and p47(phox) in human primary renal epithelial cells (HRCs).	Oxalates	117-124	secreted phosphoprotein 1	Homo sapiens	222-225	
18721209-3	2008	In the present study, we demonstrated that oxalate induces OPN expression by activating NF-kappaB in renal tubular cells.	Oxalates	43-50	secreted phosphoprotein 1	Homo sapiens	59-62	
16925768-0	2006	Oxalate ions and calcium oxalate crystal-induced up-regulation of osteopontin and monocyte chemoattractant protein-1 in renal fibroblasts.	Oxalates	0-7	secreted phosphoprotein 1	Homo sapiens	66-77	
10541281-4	1999	Oxalate-induced changes were also assessed in the expression of two genes: egr-1, a zinc-finger transcription factor, and osteopontin, a protein associated with tissue remodeling.	Oxalates	0-7	secreted phosphoprotein 1	Homo sapiens	122-133	
10541281-9	1999	This mitogenic effect offset cell loss at lower oxalate concentrations (88 microM) leading to a small but significant increase in cell number at 72 h. Treatment with oxalate also increased expression of egr-1 mRNA within 1 h, a response that was attenuated by MnTMPyP; oxalate treatment for 8 h also increased abundance of osteopontin mRNA.	Oxalates	166-173	secreted phosphoprotein 1	Homo sapiens	323-334	
10541281-9	1999	This mitogenic effect offset cell loss at lower oxalate concentrations (88 microM) leading to a small but significant increase in cell number at 72 h. Treatment with oxalate also increased expression of egr-1 mRNA within 1 h, a response that was attenuated by MnTMPyP; oxalate treatment for 8 h also increased abundance of osteopontin mRNA.	Oxalates	166-173	secreted phosphoprotein 1	Homo sapiens	323-334