PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19839830-8 2009 PJ was found to have inhibitory effects on renal tubular cell injury and oxidative stress caused by oxalate crystals by reducing ROS, iNOS, p38-MAPK, and NF-kB expression. Oxalates 100-107 mitogen activated protein kinase 14 Rattus norvegicus 140-148 29653411-4 2018 In addition, oxalate-induced p38 phosphorylation was significantly attenuated by chloroquine pretreatment but was markedly enhanced by rapamycin pretreatment, whereas the protective effect of chloroquine on rat renal tubular cell oxidative injury was partly reversed by a p38 protein kinase activator anisomycin. Oxalates 13-20 mitogen activated protein kinase 14 Rattus norvegicus 29-32 29653411-4 2018 In addition, oxalate-induced p38 phosphorylation was significantly attenuated by chloroquine pretreatment but was markedly enhanced by rapamycin pretreatment, whereas the protective effect of chloroquine on rat renal tubular cell oxidative injury was partly reversed by a p38 protein kinase activator anisomycin. Oxalates 13-20 mitogen activated protein kinase 14 Rattus norvegicus 272-275 29653411-6 2018 Taken together, our results revealed that autophagy inhibition could attenuate oxalate-induced oxidative injury of renal tubular cell and CaOx crystal depositions in the rat kidney via, at least in part, inhibiting the activation of p38 signaling pathway, thus representing a novel role of autophagy in the regulation of oxalate-induced renal oxidative injury and CaOx crystal depositions for the first time. Oxalates 79-86 mitogen activated protein kinase 14 Rattus norvegicus 233-236 29653411-6 2018 Taken together, our results revealed that autophagy inhibition could attenuate oxalate-induced oxidative injury of renal tubular cell and CaOx crystal depositions in the rat kidney via, at least in part, inhibiting the activation of p38 signaling pathway, thus representing a novel role of autophagy in the regulation of oxalate-induced renal oxidative injury and CaOx crystal depositions for the first time. Oxalates 321-328 mitogen activated protein kinase 14 Rattus norvegicus 233-236 15499208-8 2004 Both oxalate and calcium oxalate crystals selectively activate p38 mitogen-activated protein kinase in the exposed tubular cells. Oxalates 5-12 mitogen activated protein kinase 14 Rattus norvegicus 63-66