PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25477962-2	2014	In this study we investigated the effects of the small molecular agent NU6140 (inhibits CDK2 and cyclin A interaction) on human embryonic stem (hES) cells and embryonal carcinoma-derived (hEC) cells via the expression of transcription factors responsible for pluripotency.	4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide	71-77	ribosome binding protein 1	Homo sapiens	144-147	
25477962-4	2014	Both hES and hEC cells responded to NU6140 treatment by induced apoptosis and a decreased expression of NANOG, OCT4, and SOX2 in surviving cells.	4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide	36-42	ribosome binding protein 1	Homo sapiens	5-8	
25477962-5	2014	A higher sensitivity to NU6140 application in hES than hEC cells was detected.	4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide	24-30	ribosome binding protein 1	Homo sapiens	46-49	
25477962-6	2014	NU6140 treatment arrested hES and hEC cells in the G2 phase and inhibited entry into the M phase as evidenced by no significant increase in histone 3 phosphorylation.	4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide	0-6	ribosome binding protein 1	Homo sapiens	26-29