PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11574400-4 2001 Incubation with the phosphatase inhibitor okadaic acid before insulin stimulation protected against the effect of the fatty acid on PKB phosphorylation. Okadaic Acid 42-54 protein tyrosine kinase 2 beta Homo sapiens 132-135 16297906-5 2005 Okadaic acid markedly increased the co-immunoprecipitation of both the catalytic and regulatory subunits of phosphatidylinositol 3-kinase and of Akt/protein kinase B with the adrenoceptor and only marginally increases receptor association with protein kinase C epsilon. Okadaic Acid 0-12 protein tyrosine kinase 2 beta Homo sapiens 149-165 15706224-3 2005 Using Western blotting, we found that the amounts of activated PKB[pS-473] and inactivated GSK-3beta[pS-9] were increased in proportion to the progress of okadaic acid induced tau phosphorylation. Okadaic Acid 155-167 protein tyrosine kinase 2 beta Homo sapiens 63-66 15706224-4 2005 Immunocytochemistry showed that PKB[pS-473] and GSK-3beta[pS-9] immunoreactivity increased in dystrophic neurites and cell bodies in degenerating neurons after okadaic acid treatment. Okadaic Acid 160-172 protein tyrosine kinase 2 beta Homo sapiens 32-35 15706224-5 2005 Double staining with phosphospecific tau antibodies showed that PKB[pS-473] and GSK-3beta[pS-9] were colocalized with phosphospecific tau in response to okadaic acid. Okadaic Acid 153-165 protein tyrosine kinase 2 beta Homo sapiens 64-67 10373517-9 1999 In addition, the dephosphorylation of PKB was prevented by pretreatment with the phosphatase inhibitors okadaic acid and calyculin A. Okadaic Acid 104-116 protein tyrosine kinase 2 beta Homo sapiens 38-41 9112399-2 1997 In this study, we demonstrate that protein kinase B, a serine/threonine kinase stimulated by PI 3-kinase, is activated by both insulin and okadaic acid in isolated adipocytes, in parallel with their effects on Glut 4 translocation. Okadaic Acid 139-151 protein tyrosine kinase 2 beta Homo sapiens 35-51 9112399-7 1997 Our results suggest that PKB could play a role in promoting Glut 4 appearance at the cell surface following exposure of adipocytes to insulin and okadaic acid stimulation. Okadaic Acid 146-158 protein tyrosine kinase 2 beta Homo sapiens 25-28