PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12210726-5 2002 Okadaic acid stimulated osteopontin mRNA expression in several cell lines within 3 h, and the increase in osteopontin mRNA was sustained for 24 h. New protein synthesis was required for the okadaic acid-elicited increase in osteopontin mRNA expression. Okadaic Acid 190-202 secreted phosphoprotein 1 Homo sapiens 24-35 12920127-9 2003 Finally, we have determined that the proteasomal activity is required not only for phosphate-induced expression of osteopontin but also for the induction of osteopontin in response to 12-O-tetradecanoylphorbol 13-acetate and okadaic acid. Okadaic Acid 225-237 secreted phosphoprotein 1 Homo sapiens 157-168 12210726-0 2002 Okadaic acid stimulates osteopontin expression through de novo induction of AP-1. Okadaic Acid 0-12 secreted phosphoprotein 1 Homo sapiens 24-35 12210726-3 2002 Okadaic acid, a strong non-phorbol ester tumor promoter, is known to stimulate the expression of osteopontin. Okadaic Acid 0-12 secreted phosphoprotein 1 Homo sapiens 97-108 12210726-4 2002 The aim of the present study was to understand the mechanism by which okadaic acid regulates osteopontin gene expression. Okadaic Acid 70-82 secreted phosphoprotein 1 Homo sapiens 93-104 12210726-5 2002 Okadaic acid stimulated osteopontin mRNA expression in several cell lines within 3 h, and the increase in osteopontin mRNA was sustained for 24 h. New protein synthesis was required for the okadaic acid-elicited increase in osteopontin mRNA expression. Okadaic Acid 0-12 secreted phosphoprotein 1 Homo sapiens 24-35 12210726-5 2002 Okadaic acid stimulated osteopontin mRNA expression in several cell lines within 3 h, and the increase in osteopontin mRNA was sustained for 24 h. New protein synthesis was required for the okadaic acid-elicited increase in osteopontin mRNA expression. Okadaic Acid 190-202 secreted phosphoprotein 1 Homo sapiens 106-117 12210726-5 2002 Okadaic acid stimulated osteopontin mRNA expression in several cell lines within 3 h, and the increase in osteopontin mRNA was sustained for 24 h. New protein synthesis was required for the okadaic acid-elicited increase in osteopontin mRNA expression. Okadaic Acid 190-202 secreted phosphoprotein 1 Homo sapiens 106-117 12210726-8 2002 Site-directed mutagenesis and electrophoretic mobility shift assays confirmed that protein binding of the AP-1 consensus sequence is necessary for the okadaic acid-mediated osteopontin gene upregulation. Okadaic Acid 151-163 secreted phosphoprotein 1 Homo sapiens 173-184 12210726-9 2002 These results indicate that de novo induction of the oncoprotein AP-1 is required for okadaic acid-stimulated osteopontin gene upregulation. Okadaic Acid 86-98 secreted phosphoprotein 1 Homo sapiens 110-121