PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29743262-5	2018	The infiltration peaked at 12 h, but had reduced by 48 h. Testicular macrophages from MEHP-treated rats showed significantly upregulated expression of Tnfa and Il6, and the Arg1/Nos2 ratio was reduced compared to controls.	mono-(2-ethylhexyl)phthalate	86-90	tumor necrosis factor	Rattus norvegicus	151-155	
19938896-8	2010	Further, we found that the 5-LO inhibitor nordihydrogualaretic acid (NDGA) significantly reduced both MEHP-induced TNF-alpha release and MEHP-induced formation of reactive oxygen species (ROS), supporting an involvement of the 5-LO pathway in MEHP induced inflammatory reactions.	mono-(2-ethylhexyl)phthalate	102-106	tumor necrosis factor	Rattus norvegicus	115-124	
19938896-9	2010	Last, we found that MK-886, a known inhibitor of peroxisome proliferator-activated receptor alpha (PPARalpha), increased the MEHP-induced TNF-alpha response.	mono-(2-ethylhexyl)phthalate	125-129	tumor necrosis factor	Rattus norvegicus	138-147	
19938896-4	2010	First, we show that MEHP induces a dose-dependent release of the pro-inflammatory tumour necrosis factor-alpha (TNF-alpha) in AMs, giving a maximal (5-fold) increase at 0.7 mM.	mono-(2-ethylhexyl)phthalate	20-24	tumor necrosis factor	Rattus norvegicus	112-121