PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16484285-0	2006	Mono-(2-ethylhexyl) phthalate rapidly increases celsr2 protein phosphorylation in HeLa cells via protein kinase C and casein kinase 1.	mono-(2-ethylhexyl)phthalate	0-29	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	48-54	
16484285-4	2006	Within 2 h of a 1-g/kg mono-(2-ethylhexyl) phthalate (MEHP) exposure, in vivo Sertoli cell celsr2 localization was altered; celsr2 immunostaining became concentrated in the basal aspect of Sertoli cells, and then a diffuse pattern emerged.	mono-(2-ethylhexyl)phthalate	23-52	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	91-97	
16484285-4	2006	Within 2 h of a 1-g/kg mono-(2-ethylhexyl) phthalate (MEHP) exposure, in vivo Sertoli cell celsr2 localization was altered; celsr2 immunostaining became concentrated in the basal aspect of Sertoli cells, and then a diffuse pattern emerged.	mono-(2-ethylhexyl)phthalate	23-52	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	124-130	
16484285-4	2006	Within 2 h of a 1-g/kg mono-(2-ethylhexyl) phthalate (MEHP) exposure, in vivo Sertoli cell celsr2 localization was altered; celsr2 immunostaining became concentrated in the basal aspect of Sertoli cells, and then a diffuse pattern emerged.	mono-(2-ethylhexyl)phthalate	54-58	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	91-97	
16484285-4	2006	Within 2 h of a 1-g/kg mono-(2-ethylhexyl) phthalate (MEHP) exposure, in vivo Sertoli cell celsr2 localization was altered; celsr2 immunostaining became concentrated in the basal aspect of Sertoli cells, and then a diffuse pattern emerged.	mono-(2-ethylhexyl)phthalate	54-58	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	124-130	
16484285-5	2006	Because GPCRs are regulated by phosphorylation, the hypothesis that phthalate exposure induces the phosphorylation of celsr2 was tested by examining phosphorylation in celsr2-transfected HeLa cells treated with MEHP.	mono-(2-ethylhexyl)phthalate	211-215	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	118-124	
16484285-6	2006	At concentrations of 1 microM or greater, MEHP transiently increased celsr2 phosphorylation on serine/threonine residues; celsr2 phosphorylation was increased by 15 min of exposure and returned to control levels after 60 min.	mono-(2-ethylhexyl)phthalate	42-46	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	69-75	
16484285-9	2006	Inhibition of protein kinase C or casein kinase 1 prevented MEHP-induced celsr2 phosphorylation, while inhibition of protein kinase A or mitogen-activated protein kinase had no effect.	mono-(2-ethylhexyl)phthalate	60-64	cadherin EGF LAG seven-pass G-type receptor 2	Homo sapiens	73-79