PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35143864-7	2022	RESULTS: MEHP exposure significantly induced oxidative damage in BRL-3A cells, which inhibited the expression of STAT5A and promoted the expression of fibrosis related proteins MMP2, MMP9, TIMP2 and CTGF.	mono-(2-ethylhexyl)phthalate	9-13	signal transducer and activator of transcription 5A	Rattus norvegicus	113-119	
35143864-8	2022	After over-expression of STAT5A gene in BRL-3A cells, the elevated expression levels of CTGF, MMP2, MMP9 and TIMP2 induced by MEHP exposure were significantly reversed.	mono-(2-ethylhexyl)phthalate	126-130	signal transducer and activator of transcription 5A	Rattus norvegicus	25-31	
35143864-9	2022	CONCLUSION: This study demonstrated that MEHP exposure inhibited the expression of STAT5A by causing oxidative damage in BRL-3A hepatocytes, thus accelerating the expression of key molecules in fibrosis and promoting the occurrence of liver fibrosis.	mono-(2-ethylhexyl)phthalate	41-45	signal transducer and activator of transcription 5A	Rattus norvegicus	83-89	
31491605-0	2019	Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.	mono-(2-ethylhexyl)phthalate	0-27	signal transducer and activator of transcription 5A	Rattus norvegicus	72-77	
31491605-0	2019	Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.	mono-(2-ethylhexyl)phthalate	29-33	signal transducer and activator of transcription 5A	Rattus norvegicus	72-77	
31491605-2	2019	We aim to clarify the effects of JAK2/STAT5 pathway on lipid accumulation induced by MEHP and the role of oxidation stress in NAFLD.	mono-(2-ethylhexyl)phthalate	85-89	signal transducer and activator of transcription 5A	Rattus norvegicus	38-43	
31491605-7	2019	MEHP down-regulated the expression and inhibited the activation of JAK2/STAT5.	mono-(2-ethylhexyl)phthalate	0-4	signal transducer and activator of transcription 5A	Rattus norvegicus	72-77	
31491605-12	2019	Therefore, we concluded that MEHP led to lipid accumulation through inhibiting JAK2/STAT5 pathway, resulted in damaging liver parenchyma and NAFLD by aggravating oxidation stress.	mono-(2-ethylhexyl)phthalate	29-33	signal transducer and activator of transcription 5A	Rattus norvegicus	84-89