PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33029813-0 2021 Activation of forkhead box O3a by mono(2-ethylhexyl)phthalate and its role in protection against mono(2-ethylhexyl)phthalate-induced oxidative stress and apoptosis in human cardiomyocytes. mono-(2-ethylhexyl)phthalate 34-61 forkhead box O3 Homo sapiens 14-30 33029813-0 2021 Activation of forkhead box O3a by mono(2-ethylhexyl)phthalate and its role in protection against mono(2-ethylhexyl)phthalate-induced oxidative stress and apoptosis in human cardiomyocytes. mono-(2-ethylhexyl)phthalate 97-124 forkhead box O3 Homo sapiens 14-30 33029813-2 2021 The aim of the present study was to investigate the role of forkhead box O3a (FOXO3a) in MEHP-induced human AC16 cardiomyocyte injuries. mono-(2-ethylhexyl)phthalate 89-93 forkhead box O3 Homo sapiens 60-76 33029813-2 2021 The aim of the present study was to investigate the role of forkhead box O3a (FOXO3a) in MEHP-induced human AC16 cardiomyocyte injuries. mono-(2-ethylhexyl)phthalate 89-93 forkhead box O3 Homo sapiens 78-84 33029813-4 2021 The expression of FOXO3a and its target genes, mitochondrial superoxide dismutase (Mn-SOD) and apoptosis repressor with caspase recruitment domain (ARC), increased after MEHP exposure, but the expression of p-FOXO3a protein was decreased. mono-(2-ethylhexyl)phthalate 170-174 forkhead box O3 Homo sapiens 18-24 33029813-4 2021 The expression of FOXO3a and its target genes, mitochondrial superoxide dismutase (Mn-SOD) and apoptosis repressor with caspase recruitment domain (ARC), increased after MEHP exposure, but the expression of p-FOXO3a protein was decreased. mono-(2-ethylhexyl)phthalate 170-174 forkhead box O3 Homo sapiens 209-215 33029813-5 2021 Overexpression of FOXO3a decreased the production of ROS and the apoptosis rate induced by MEHP, and the expression of Mn-SOD and ARC was further increased after MEHP exposure. mono-(2-ethylhexyl)phthalate 91-95 forkhead box O3 Homo sapiens 18-24 33029813-5 2021 Overexpression of FOXO3a decreased the production of ROS and the apoptosis rate induced by MEHP, and the expression of Mn-SOD and ARC was further increased after MEHP exposure. mono-(2-ethylhexyl)phthalate 162-166 forkhead box O3 Homo sapiens 18-24 33029813-6 2021 In contrast, knockdown of FOXO3a resulted in increased ROS production and apoptosis and suppressed the expression of Mn-SOD and ARC in the presence of MEHP. mono-(2-ethylhexyl)phthalate 151-155 forkhead box O3 Homo sapiens 26-32 33029813-9 2021 Activation of FOXO3a defends against MEHP-induced oxidative stress and apoptosis by upregulating the expression of Mn-SOD and ARC in AC16 cardiomyocytes. mono-(2-ethylhexyl)phthalate 37-41 forkhead box O3 Homo sapiens 14-20