PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25592707-0 2015 Synthesis and in vitro characterization of cinnoline and benzimidazole analogues as phosphodiesterase 10A inhibitors. cinnoline 43-52 phosphodiesterase 10A Homo sapiens 84-105 24789056-0 2014 Structural findings of cinnolines as anti-schizophrenic PDE10A inhibitors through comparative chemometric modeling. cinnoline 23-33 phosphodiesterase 10A Homo sapiens 56-62 24789056-4 2014 2D-QSAR, HQSAR, pharmacophore mapping, molecular docking, and 3D-QSAR analyses were performed on 81 cinnoline derivatives having PDE10A inhibitory activity. cinnoline 100-109 phosphodiesterase 10A Homo sapiens 129-135 23044369-2 2012 An analysis of the PDE3 catalytic domain compared to the co-crystal structure of cinnoline analog 1 in PDE10A revealed two areas of structural differences in the active sites and suggested areas on the scaffold that could be modified to exploit those unique structural features. cinnoline 81-90 phosphodiesterase 10A Homo sapiens 103-109