PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35499148-0	2022	miRNA-34c-5p targets Fra-1 to inhibit pulmonary fibrosis induced by silica through p53 and PTEN/PI3K/Akt signaling pathway.	Silicon Dioxide	68-74	phosphatase and tensin homolog	Homo sapiens	91-95	
35499148-8	2022	In addition, through interaction with PTEN/p53 it inhibits the proliferation and migration of human bronchial epithelial cells stimulated by silica, and promotes cell apoptosis, thereby preventing EMT.	Silicon Dioxide	141-147	phosphatase and tensin homolog	Homo sapiens	38-42	
33985625-0	2021	[Role of PTEN in FAK and alpha-SMA protein levels changes in human embryonic lung fibroblasts induced by silica].	Silicon Dioxide	105-111	phosphatase and tensin homolog	Homo sapiens	9-13	
33985625-1	2021	OBJECTIVE: To investigate the roles of phosphatase and tensin homolog deleted on chromosome 10(PTEN) in focal adhesion kinase(FAK) and alpha-smooth muscle actin(alpha-SMA) protein levels changes in human embryonic lung fibroblasts(HELFs) induced by silica.	Silicon Dioxide	249-255	phosphatase and tensin homolog	Homo sapiens	95-99	
33985625-13	2021	Compared with the control group of silica treated HELFs, the expression levels of PTEN and p-PTEN at 12 h and 24 h were significantly decreased(PTEN: 0.	Silicon Dioxide	35-41	phosphatase and tensin homolog	Homo sapiens	82-86	
33985625-13	2021	Compared with the control group of silica treated HELFs, the expression levels of PTEN and p-PTEN at 12 h and 24 h were significantly decreased(PTEN: 0.	Silicon Dioxide	35-41	phosphatase and tensin homolog	Homo sapiens	93-97	
33985625-13	2021	Compared with the control group of silica treated HELFs, the expression levels of PTEN and p-PTEN at 12 h and 24 h were significantly decreased(PTEN: 0.	Silicon Dioxide	35-41	phosphatase and tensin homolog	Homo sapiens	93-97	
24964613-0	2014	[Effects of ceruloplasmin/PTEN on histone modifications induced by silica].	Silicon Dioxide	67-73	phosphatase and tensin homolog	Homo sapiens	26-30	
24754934-0	2014	[The effects of ceruloplasmin in PI3K/PTEN cell signaling pathway change induced by silica].	Silicon Dioxide	84-90	phosphatase and tensin homolog	Homo sapiens	38-42	
24754934-1	2014	OBJECTIVE: To investigate the roles of ceruloplasmin (Cp) in PI3K/PTEN cell signaling pathway change in human embryonic lung fibroblasts (HELFs) induced by silica.	Silicon Dioxide	156-162	phosphatase and tensin homolog	Homo sapiens	66-70	
24754934-5	2014	MTT assay was used to detect the effects of Cp on silica-induced cell proliferation after inhibiting PTEN and p85.	Silicon Dioxide	50-56	phosphatase and tensin homolog	Homo sapiens	101-105	
24754934-7	2014	RESULTS: After inhibition of PTEN, the high levels of p85 induced by 100 microg/ml silica with 30 microg/ml Cp were markedly decreased (P<0.05).	Silicon Dioxide	83-89	phosphatase and tensin homolog	Homo sapiens	29-33	
24754934-10	2014	CONCLUSION: Cp could further strengthened silica-induced cell proliferation by PI3K/AKT/MAPK cell signaling pathway, of which the level of p85 was regulated by PTEN.	Silicon Dioxide	42-48	phosphatase and tensin homolog	Homo sapiens	160-164	
27621875-2	2016	Our previous study has demonstrated that silica mediates the activation of phosphatidylinositol 3-kinase (PI3K)/phosphatase and tensin homolog deleted on chromosome 10 (PTEN)/serine or threonine kinase (AKT)/mitogen-activated protein kinases (MAPK)/AP-1 pathway in human embryo lung fibroblasts (HELFs).	Silicon Dioxide	41-47	phosphatase and tensin homolog	Homo sapiens	169-173