PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31587517-0 2020 Perfusion process combining low temperature and valeric acid for enhanced recombinant factor VIII production. n-pentanoic acid 48-60 coagulation factor VIII Homo sapiens 86-97 31587517-5 2020 Increases in cell specific productivity (qp ) up to 2.4-fold (FVIII concentration) and up to 3.0-fold (FVIII biological activity) were obtained at 31 C with VA compared to the control at 37 C. Biological activity is the most important quality attribute for FVIII and was positively affected by mild hypothermia in combination with the chemical inducer. n-pentanoic acid 157-159 coagulation factor VIII Homo sapiens 62-67 31587517-5 2020 Increases in cell specific productivity (qp ) up to 2.4-fold (FVIII concentration) and up to 3.0-fold (FVIII biological activity) were obtained at 31 C with VA compared to the control at 37 C. Biological activity is the most important quality attribute for FVIII and was positively affected by mild hypothermia in combination with the chemical inducer. n-pentanoic acid 157-159 coagulation factor VIII Homo sapiens 103-108 31587517-5 2020 Increases in cell specific productivity (qp ) up to 2.4-fold (FVIII concentration) and up to 3.0-fold (FVIII biological activity) were obtained at 31 C with VA compared to the control at 37 C. Biological activity is the most important quality attribute for FVIII and was positively affected by mild hypothermia in combination with the chemical inducer. n-pentanoic acid 157-159 coagulation factor VIII Homo sapiens 103-108