PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2253091-1 1990 Human mast cell tryptase was purified from lung tissue by high salt extraction, ammonium sulphate precipitation, octyl Sepharose and heparin-agarose chromatography. Heparin 133-140 tryptase delta 1 Homo sapiens 6-24 12701115-3 2003 Eosinophil granule proteins and purified eosinophil peroxidase markedly reduced the anticoagulant properties of the mast cell tryptase/heparin complex. Heparin 135-142 tryptase delta 1 Homo sapiens 116-134 10334872-5 1999 Heparin, at high concentrations, can prevent the inhibition of tryptase by MPO. Heparin 0-7 tryptase delta 1 Homo sapiens 63-71 10334872-7 1999 These data suggest that MPO inhibits tryptase by interfering with the heparin stabilization of tryptase tetramer. Heparin 70-77 tryptase delta 1 Homo sapiens 37-45 10334872-7 1999 These data suggest that MPO inhibits tryptase by interfering with the heparin stabilization of tryptase tetramer. Heparin 70-77 tryptase delta 1 Homo sapiens 95-103 2449172-12 1987 The mast cell proteoglycans heparin and chondroitin sulphate E, by virtue of containing the naturally occurring glycosaminoglycans of highest negative charge density, may play a major role in the regulation of mast cell tryptase activity in vivo. Heparin 28-35 tryptase delta 1 Homo sapiens 210-228