PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2996528-4	1985	Purified rat neutrophil LTA4 hydrolase incubated with 100 microM leukotriene A5 produced 22 nmol LTB5/min/mg protein and when incubated with 100 microM leukotriene A4 produced 50 nmol LTB4/min/mg protein.	Leukotriene B4	184-188	leukotriene A4 hydrolase	Rattus norvegicus	24-38	
23986401-3	2013	In both clinical tissue and the SU5416 (SU)/athymic rat model of severe PH, we found that the accumulated macrophages expressed high levels of leukotriene A4 hydrolase (LTA4H), the biosynthetic enzyme for leukotriene B4 (LTB4).	Leukotriene B4	205-219	leukotriene A4 hydrolase	Rattus norvegicus	143-167	
23986401-3	2013	In both clinical tissue and the SU5416 (SU)/athymic rat model of severe PH, we found that the accumulated macrophages expressed high levels of leukotriene A4 hydrolase (LTA4H), the biosynthetic enzyme for leukotriene B4 (LTB4).	Leukotriene B4	205-219	leukotriene A4 hydrolase	Rattus norvegicus	169-174	
21274744-3	2012	Leukotriene B(4) (LTB(4)) is an inflammatory mediator, and its production is mediated through two specific enzymes--lipooxygenase (LOX) and leukotriene A(4) hydrolase (LTA(4)H).	Leukotriene B4	0-13	leukotriene A4 hydrolase	Rattus norvegicus	140-166	
21274744-3	2012	Leukotriene B(4) (LTB(4)) is an inflammatory mediator, and its production is mediated through two specific enzymes--lipooxygenase (LOX) and leukotriene A(4) hydrolase (LTA(4)H).	Leukotriene B4	0-13	leukotriene A4 hydrolase	Rattus norvegicus	168-175	
21342324-2	2011	Leukotriene B4 (LTB4) is a bioactive eicosanoid and macrophage and has two key enzymes for LTB4 synthesis, 5-lipoxygenase and leukotriene A4 (LTA4) hydrolase.	Leukotriene B4	0-14	leukotriene A4 hydrolase	Rattus norvegicus	126-157	
21342324-2	2011	Leukotriene B4 (LTB4) is a bioactive eicosanoid and macrophage and has two key enzymes for LTB4 synthesis, 5-lipoxygenase and leukotriene A4 (LTA4) hydrolase.	Leukotriene B4	16-20	leukotriene A4 hydrolase	Rattus norvegicus	126-157	
18157165-1	2008	BACKGROUND AND PURPOSE: Leukotriene B(4) (LTB(4)), formed by the sequential actions of the 5-lipoxygenase (5-LO) and leukotriene A(4) hydrolase (LTA(4)H), is a pro-inflammatory mediator implicated in the pathogenesis of inflammatory bowel disease.	Leukotriene B4	24-37	leukotriene A4 hydrolase	Rattus norvegicus	117-143	
18157165-1	2008	BACKGROUND AND PURPOSE: Leukotriene B(4) (LTB(4)), formed by the sequential actions of the 5-lipoxygenase (5-LO) and leukotriene A(4) hydrolase (LTA(4)H), is a pro-inflammatory mediator implicated in the pathogenesis of inflammatory bowel disease.	Leukotriene B4	24-37	leukotriene A4 hydrolase	Rattus norvegicus	145-152	
12865451-3	2003	Leukotriene A4 hydrolase (LTA4H), a protein overexpressed in EAC in this model, is a rate-limiting enzyme in the biosynthesis of leukotriene B4 (LTB4), a potent inflammatory mediator.	Leukotriene B4	129-143	leukotriene A4 hydrolase	Rattus norvegicus	0-24	
12865451-3	2003	Leukotriene A4 hydrolase (LTA4H), a protein overexpressed in EAC in this model, is a rate-limiting enzyme in the biosynthesis of leukotriene B4 (LTB4), a potent inflammatory mediator.	Leukotriene B4	129-143	leukotriene A4 hydrolase	Rattus norvegicus	26-31	
12865451-3	2003	Leukotriene A4 hydrolase (LTA4H), a protein overexpressed in EAC in this model, is a rate-limiting enzyme in the biosynthesis of leukotriene B4 (LTB4), a potent inflammatory mediator.	Leukotriene B4	145-149	leukotriene A4 hydrolase	Rattus norvegicus	0-24	
12865451-3	2003	Leukotriene A4 hydrolase (LTA4H), a protein overexpressed in EAC in this model, is a rate-limiting enzyme in the biosynthesis of leukotriene B4 (LTB4), a potent inflammatory mediator.	Leukotriene B4	145-149	leukotriene A4 hydrolase	Rattus norvegicus	26-31	
11451962-1	2001	The synthesis of leukotriene B(4) from arachidonic acid requires the sequential action of two enzymes: 5-lipoxygenase and leukotriene A(4) hydrolase.	Leukotriene B4	17-30	leukotriene A4 hydrolase	Rattus norvegicus	122-148	
10601658-1	1999	Leukotriene A(4) (LTA(4)) hydrolase is essential for the conversion of LTA(4) to LTB(4), an inflammatory lipid mediator.	Leukotriene B4	81-84	leukotriene A4 hydrolase	Rattus norvegicus	18-35