PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6420041-4	1984	Since alpha-difluoromethylornithine (DFMO) and methylglyoxal-bis-guanylhydrazone (MGBG) are irreversible and competitive inhibitors of ODC and SAMDC, respectively, they were tested as single agents and in combination on a transplantable rapidly growing and hormone-resistant G subline of the Dunning R-3327 rat prostatic adenocarcinoma.	Eflornithine	6-35	adenosylmethionine decarboxylase 1	Rattus norvegicus	143-148	
1415709-12	1992	Treatment with DL-alpha-difluoromethylornithine (DFMO), a specific ODC inhibitor, prevented the increases in both cellular putrescine levels and SAMDC activity in asparagine- and serum-treated cells.	Eflornithine	15-47	adenosylmethionine decarboxylase 1	Rattus norvegicus	145-150	
1415709-12	1992	Treatment with DL-alpha-difluoromethylornithine (DFMO), a specific ODC inhibitor, prevented the increases in both cellular putrescine levels and SAMDC activity in asparagine- and serum-treated cells.	Eflornithine	49-53	adenosylmethionine decarboxylase 1	Rattus norvegicus	145-150	
1415709-13	1992	In the presence of DFMO, exogenous putrescine returned SAMDC activity toward control levels but had no effect on ODC.	Eflornithine	19-23	adenosylmethionine decarboxylase 1	Rattus norvegicus	55-60	
7899459-9	1995	In contrast, the azaserine-induced significant increase in hepatic putrescine was lower and transient, was accompanied by an increase in ODC and SAM-DC, and was completely inhibited by simultaneous DFMO treatment but not by MDL 72527.	Eflornithine	198-202	adenosylmethionine decarboxylase 1	Rattus norvegicus	145-151	
2114097-1	1990	S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO).	Eflornithine	169-192	adenosylmethionine decarboxylase 1	Rattus norvegicus	0-34	
2114097-1	1990	S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO).	Eflornithine	169-192	adenosylmethionine decarboxylase 1	Rattus norvegicus	36-44	
2114097-1	1990	S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO).	Eflornithine	194-198	adenosylmethionine decarboxylase 1	Rattus norvegicus	0-34	
2114097-1	1990	S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO).	Eflornithine	194-198	adenosylmethionine decarboxylase 1	Rattus norvegicus	36-44	
2114097-6	1990	The shift of the AdoMetDC message into large polysomes occurred within 18 h after addition of DFMO to the cultures and could be reversed by adding exogenous putrescine.	Eflornithine	94-98	adenosylmethionine decarboxylase 1	Rattus norvegicus	17-25	
6420041-4	1984	Since alpha-difluoromethylornithine (DFMO) and methylglyoxal-bis-guanylhydrazone (MGBG) are irreversible and competitive inhibitors of ODC and SAMDC, respectively, they were tested as single agents and in combination on a transplantable rapidly growing and hormone-resistant G subline of the Dunning R-3327 rat prostatic adenocarcinoma.	Eflornithine	37-41	adenosylmethionine decarboxylase 1	Rattus norvegicus	143-148